Increased alcohol use among pregnant and postpartum women during the COVID-19 pandemic was associated with autonomic nervous system dysregulation, known to negatively affect resilience to change and further exacerbate the risk of stress-related mental health disorders and substance use, a new study suggests. The findings, although preliminary, underline the potential for a new clinical biomarker and novel personalized mobile health apps in facilitating treatment interventions. Previous research linked the pandemic to increased stress levels and drinking, including in pregnant and postpartum women. Alcohol use, and stress-related conditions such as depression and anxiety, are associated with dysregulation in the feedback loop between the body and the brain. This process involves the peripheral autonomic nervous system, which regulates the heartbeat. Healthy, resilient people tend to have higher heart rate variability than people with stress and substance use disorders. Heart rate variab