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Children’s Hospital Los Angeles Researchers Probe Immune Microenvironment to Prevent Pediatric Liver Transplant Rejection

April 16, 2024 sarah JonasResearch Results

Children with liver transplants must take immunosuppressant medications for life. To maintain tolerance of the transplanted liver, doctors treat transplant rejection and conduct ongoing maintenance immunosuppression by increasing dosages of medication enough to counteract rejection. CHLA researchers are developing an imaging panel that identifies the cell types implicated in transplant rejection.

A Potential Biomarker for Pediatric Acute Liver Failure

June 2, 2023 sarah JonasResearch Results

A tiny population of T-cells could serve as a much-needed biomarker—and a potential therapeutic target—for pediatric acute liver failure, according to new research from Children’s Hospital Los Angeles.