JMIR Publications recently published “Dissemination and Implementation of a Google Apple Exposure Notification System for COVID-19 Risk Mitigation at a National Public University: Protocol for a Pilot Evaluation Study in a Real-World Setting” in JMIR Research Protocols which reported that this paper describes the protocol for South Carolina Safer Together, developed by Clemson University to design, deploy, and evaluate multilevel communication and dissemination and implementation (D&I) strategies in line with recommendations from governmental and educational agencies to mitigate the risk of exposure to COVID-19.