Innovative Light-Driven Enzymatic Biosystem for the Synthesis of Natural Terpenoids

In a recent study, researchers from China have developed a light-driven in vitro enzymatic system to produce α-farnesene, a useful natural terpenoid, from methanol. By optimizing and coupling thirteen biocatalytic reactions, and using natural thylakoid membranes, they achieved a significant α-farnesene production using methanol and glycolaldehyde as source materials.

Sandalwood Oil By-product Prevents Prostate Cancer Development in Mice

Sandalwood oil has been used worldwide for centuries. Now, a study is the first to demonstrate in vivo the chemo-preventive properties of a by-product of the oil in a mouse model. Results show administering alpha-santalol reduced visible prostate tumors, protected the normal tissue, and delayed progression from a precancerous condition to a high-grade form of cancer. These findings are significant because mortality in prostate cancer patients is mainly attributable to advanced stages of the disease.