Surprising findings from a study in Nature Medicine suggest that the burden of C. diff infection may be less a matter of hospital transmission and more a result of characteristics associated with the patients themselves.
Tag: C Difficile
Experts discuss benefits and risks of different guideline-approved treatment approaches for C. difficile infection
In a new Annals ‘Beyond the Guidelines’ feature, an infectious diseases specialist and a gastroenterologist discuss the benefits and risks of different treatment approaches for Clostridioides difficile infection (CDI). The experts consider clinical practice guidelines and provide rationale for how their recommendations may or may not fall within those guidelines. All ‘Beyond the Guidelines’ features are based on the Department of Medicine Grand Rounds at Beth Israel Deaconess Medical Center (BIDMC) in Boston and include print, video, and educational components published in Annals of Internal Medicine. A CME/MOC activity accompanies each article.
Researchers Examine Dynamics of C. Difficile Toxins and How Leaky Gut Affects Toxicity
Article title: A leaky human colon model reveals uncoupled apical/basal cytotoxicity in early Clostridioides difficile toxin exposure Authors: Meryem T. Ok, Jintong Liu, R. Jarrett Bliton, Caroline M. Hinesley, Ekaterina Ellyce T. San Pedro, Keith A. Breau, Ismael Gomez-Martinez, Joseph…