Microglia Might Lessen Seizure Severity in Epilepsy

Article title: Microglia depletion exacerbates acute seizures and hippocampal neuronal degeneration in mouse models of epilepsy

Authors: Mei Liu, Lijuan Jiang, Min Wen, Yue Ke, Xiangzhen Tong, Weiyuan Huang, Rongqing Chen

From the authors: “Our study indicates that microglia are innately ready to quench acute seizures and protect neurons from excitotoxicity-induced degeneration.”

This study is highlighted as one of October’s “best of the best” as part of the American Physiological Society’s APSselect program.