Tissue- and Cell-specific Properties of Specialized Cells Affect How Quickly Tumors Form in Intestinal Cancer

Article title: Tissue and cell specific properties of enterochromaffin cells affect the fate of tumorigenesis toward non-endocrine adenocarcinoma of the small intestine

Authors: Yoshitatsu Sei, Jianying Feng, Xilin Zhao, Pradeep Dagur, J. Philip McCoy, Juanita L. Merchant, Stephen A. Wank

From the authors: “These results suggest that tissue- and cell-specific properties of [enterochromaffin (EC)] cells affect the fate and rate of tumorigenesis induced by genetic alterations and provide important insights into EC cell-derived tumorigenesis.”

This study is highlighted as one of February’s “best of the best” as part of the American Physiological Society’s APSselect program.