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UrduUsing a trial of persons with monoclonal gammopathy of undetermined significance (MGUS), researchers developed a prediction model that accurately predicts the presence of 10 percent or more bone marrow plasma cells (BMPC) and therefore a diagnosis of smoldering multiple myeloma (SMM) or multiple myeloma (MM) by bone marrow criteria in persons presumed to have MGUS.
Tag: smoldering myeloma
Whole Genome Sequencing Offers New Diagnostic Insights for Multiple Myeloma Precursor Conditions
In a study published in Nature Communications, researchers at Sylvester Comprehensive Cancer Center have shown that whole genome sequencing can help determine which patients with a multiple myeloma precursor condition, called MGUS or smoldering myeloma, progress to full-blown cancer
Immune system changes occur early in development of multiple myeloma, study finds
Long before multiple myeloma becomes a malignant disease, the collection of immune system cells and signal carriers amid the tumor cells undergoes dramatic shifts, with alterations in both the number and type of immune cells, researchers at Dana-Farber Cancer Institute, the Broad Institute of MIT and Harvard, and Massachusetts General Hospital (MGH) report in a new study.