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Molecule known to slow inflammation linked to scleroderma, could be treatment target

March 9, 2023 sarah JonasResearch Results

A molecule that was until recently known as a brake on inflammation has now been implicated in fibrosis in scleroderma patients.

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Article title: Fibronectin-EDA accumulates via reduced ubiquitination downstream of toll-like receptor 9 activation in SSc-ILD fibroblasts Authors: Ferhan Tuncer, Melissa Bulik, John Villandre, Travis Lear, Yanwen Chen, Beyza Tuncer, Daniel J. Kass, Eleanor Valenzi, Christina Morse, John Sembrat II, Robert…