UC Irvine-led study links metabolism changes in certain brain cells to Huntington’s disease

Irvine, Calif., Dec. 21, 2022 — A research team led by the University of California, Irvine has linked the mutation that causes Huntington’s disease to developmental deficits in the brain’s oligodendrocyte cells that are caused by changes in metabolism. They found that high doses of thiamine and biotin can restore normal processes.