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Surprising discovery by UCI-led team links Piezo1 and cholesterol during brain development

September 7, 2022 sarah JonasResearch Results

A new University of California, Irvine-led study reveals how mechanical forces and tissue mechanics influence the morphology of the developing brain, and establishes a direct link in neural stem cells between Piezo1, a mechanically-activated ion channel, and intracellular cholesterol levels during neural development.