Searching for the optimal precondition procedure for mesenchymal stem/stromal cell treatment: Facts and perspectives

Mesenchymal stem/stromal cells are potential optimal cell sources for stem cell therapies, and pretreatment has proven to enhance cell vitality and function. In a recent publication, Li et al explored a new combination of pretreatment conditions. Here, we present an editorial to comment on their work and provide our view on mesenchymal stem/stromal cell precondition.

Key Words: Mesenchymal stem cell, Precondition, Hypoxia, Inflammation

Core Tip: Mesenchymal stem/stromal cells are important for stem cell therapies, and their vitality and function can be enhanced by hypoxia pretreatment. A novel combination of pretreatment was raised by Li et al. Here, we comment on their work and discuss related topics in this area.



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