COVID-19 Patients Have Impaired Mitochondrial and Metabolic Function

Article title: Mitochondrial metabolic manipulation by SARS-CoV-2 in peripheral blood mononuclear cells of COVID-19 patients

Authors: Saima Ajaz, Mark J. McPhail, Keshav K. Singh, Salma Mujib, Francesca M. Trovato, Salvatore Napoli, Kosh Agarwal

From the authors: “Our study identifies the important metabolic alteration in live cells from COVID-19 patients. It paves the way to investigate whether restoring mitochondrial function and/or targeting glycolysis with new or existing drugs can potentially be used for treatment for COVID-19 patients.” 

This study is highlighted as one of January’s “best of the best” as part of the American Physiological Society’s APSselect program.