High Potassium May Interfere with Electrolyte Balance in Kidneys

Article title: WNKs are potassium-sensitive kinases

Authors: John M. Pleinis, Logan Norrell, Radha Akella, John M. Humphreys, Haixia He, Qifei Sun, Feng Zhang, Jason Sosa-Pagan, Daryl E. Morrison, Jeffrey N. Schellinger, Laurie K. Jackson, Elizabeth J. Goldsmith, Aylin R. Rodan

From the authors: “Here, we demonstrate that high potassium concentrations inhibit the activity of Drosophila and mammalian WNKs expressed in the fly Malpighian tubule.” 

This study is highlighted as one of March’s “best of the best” as part of the American Physiological Society’s APSselect program.