Key Words: Wharton’s jelly mesenchymal stem cells; Vascular endothelial growth factor; Osteogenesis; Angiogenesis; Diabetic bone regeneration
Core Tip: Both osteogenesis and angiogenesis are closely related to bone regeneration. Diabetes mellitus normally impairs angiogenesis, which leads to diabetic bone regeneration deficiency. Wharton’s jelly mesenchymal stem cells not only possess the ability to differentiation into osteoblasts, but also produce a crucial secretory factor (vascular endothelial growth factor) to promote angiogenesis. Thus, Wharton’s jelly mesenchymal stem cell is expected to exert more vital role in improving diabetic bone regeneration.
- Citation: Zheng S, Hu GY, Li JH, Li YK. Potential plausible role of Wharton’s jelly mesenchymal stem cells for diabetic bone regeneration. World J Stem Cells 2024; 16(8): 824-826
- URL: https://www.wjgnet.com/1948-0210/full/v16/i8/824.htm
- DOI: https://dx.doi.org/10.4252/wjsc.v16.i8.824