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UrduA new study led by researchers at The University of Texas MD Anderson Cancer, University of California, Irvine and Baylor College of Medicine has created the world’s largest and most comprehensive map of normal breast tissue, providing an unprecedented understanding of mammary biology that may help identify therapeutic targets for diseases such as breast cancer. The Human Breast Cell Atlas, published today in Nature, used single-cell and spatial genomic methods to profile more than 714,000 cells from 126 women. The breast atlas highlights 12 major cell types and 58 biological cell states, and identifies differences based on ethnicity, age and the menopause status of healthy women.
Tag: Human Cell Atlas
Novel Cell Atlas for Multiple Human Tissues Reveals Discoveries Underlying Complex Diseases
Scientists from the Broad Institute of MIT and Harvard have developed a first-of-its-kind cross-tissue cell atlas, and in collaboration with researchers at Mass Eye and Ear, have uncovered new clues for specific cell types and genes involved in complex diseases. In a new study published May 12 in Science, researchers described for the first time how their novel cross-tissue cell atlas derived from an analysis of nuclei from 25 frozen samples from 8 tissue types may increase understanding of the cellular and genetic underpinnings of complex diseases, including heart disease and cancers.