Experimental microbially assisted chemolithotrophy provides an opportunity to trace the putative bioalteration processes of the Martian crust. A study on the Noachian Martian breccia Northwest Africa (NWA) 7034 composed of ancient (ca. 4.5 Gyr old) crustal materials from Mars, led by ERC grantee Tetyana Milojevic from the Faculty of Chemistry of the University of Vienna, now delivered a unique prototype of microbial life experimentally designed on a real Martian material. As the researchers show in the current issue of “Nature Communications Earth and Environment”, this life of a pure Martian design is a rich source of Martian-relevant biosignatures.