Study Explores Vitamin D Regulation of Bone Cell Proliferation

Article title: Downregulation of the Ca2+-activated K+ channel KCa3.1 in mouse preosteoblast cells treated with vitamin D receptor agonist

Authors: Hiroaki Kito, Haruka Morihiro, Yuka Sakakibara, Kyoko Endo, Junko Kajikuri, Takayoshi Suzuki, Susumu Ohya

From the authors: “Our results showed that decreased expression of the intermediate-conductance Ca2+-activated K+ channel KCa3.1 is one of the key events in the suppression of osteoblastic cell proliferation rate by treatment with a [vitamin D receptor] agonist.” 

This study is highlighted as one of August’s “best of the best” as part of the American Physiological Society’s APSselect program.

Original post https://alertarticles.info