The DART can lessen the risks of infection associated with procedures such as suctioning, intubation and extubation by providing an extra layer of protection between the healthcare workers and the patient. It also helps to limit environmental contamination, which can be a source of transmission.
The NUS team was led by Professor Freddy Boey, NUS Deputy President (Innovation & Enterprise), and Associate Professor Yen Ching-Chiuan, Co-Director of the Keio-NUS CUTE Center. The team comprises Dr Alfred Chia from NUS Department of Biomedical Engineering, Mr Eason Chow from Keio-NUS CUTE Center, doctoral student Mr Raymond Hon from the NUS Division of Industrial Design as well as researchers from the NUS Faculty of Engineering. The NUS team worked with Dr Deborah Khoo, Dr Wong Weng Hoa, Associate Professor Ti Lian Kah and Associate Professor Sophia Ang from the NUH Department of Anaesthesia. The multi-disciplinary team took less than two months to develop DART and validate its performance.
“The quick invention and deployment of DART was made possible through a close collaboration between the NUS and NUH teams, which allowed multiple refinements to be made to the prototypes within a very short time. The NUS team was able to come up with the various designs while adhering to the restrictions of the circuit breaker period, and found different ways to address design and performance related challenges when many resources were not available. The NUH team was instrumental in testing our prototypes in a clinical setting, allowing us to interactively and rapidly refine the performance of the device,” shared Prof Boey.
Extra protection for frontline healthcare workers
The COVID-19 pandemic dramatically increased the need for infection control when intubating patients. Intubation is the placement of a flexible plastic tube into the windpipe to maintain an open airway or to serve as a conduit through which to administer certain drugs. The removal of this plastic tube is known as extubation. These are risky procedures that may put healthcare workers in danger of becoming infected.
Evidence from the Severe Acute Respiratory Syndrome (SARS) outbreak in 2003 showed that healthcare workers involved in intubation were more likely to contract the disease compared with those who did not. This risk has similar implications for the current coronavirus outbreak, affecting anaesthesiologists, operating theatre staff, intensive care unit staff, and even first responders who are required to intubate collapsed patients in the COVID-19 general ward.
Dr Khoo, a Consultant at the NUH Department of Anaesthesia, said, “Healthcare workers caring for patients run the risk of being exposed to known, suspected, or even asymptomatic COVID-19 patients. The DART serves as an additional physical barrier to infection and provides enhanced protection for healthcare staff at a time when they need it the most, giving us greater peace of mind and enabling care to continue safely for both patients and healthcare workers in the hospitals.”
Practical and versatile solution
The DART is a portable, tent-like structure that that can be placed around the patient’s head when intubating or extubating. It weighs three kilograms, and can be folded into a flat structure measuring around 51 centimetres by 55 centimetres, with a thickness of three centimetres, making it easy to transport, store and sterilise. It is also simple and fast to set up.
The device features transparent polycarbonate panels, 3D printed nylon joints and Delrin inserts. These durable materials were chosen by the NUS team to enable the device to be sterilised by all standard forms of decontamination used in hospitals, such as elevated temperature autoclaving, and using alcohol of 70 per cent concentration. This facilitates the reusability of the device, and eliminates the risk of cross-contamination.
Arm access ports are situated on the back and side panels of the device. The snap-on flanges allow the attachment of disposable sleeves or diaphragms. This addresses the concern of the arm ports being high risk areas of contamination, and gives the healthcare workers the option to use either sleeved or diaphragm seals – materials easily available in hospitals – according to their preference. The elliptical shape of the access ports gives the user more leeway for arm movements and to manoeuvre, which are important in handling the patient.
A key feature of the DART is its ability to direct air within itself through a High Efficiency Particulate Air (HEPA) filter. It has a set of connectors that enables suction from a central vacuum system, or by a battery-operated fan attached to a HEPA filter. The negative pressure generated reduces leakage of exhaled aerosols or droplets from the patient out of the confines of the DART.
Preliminary findings by the research team showed that the DART performs its barrier function as designed, and the exhaust function via the HEPA filter gives additional assurance to the user.
Prototype testing in Singapore hospitals
The research team has produced 25 prototypes which are being tested in different departments and hospitals of the National University Health System (namely NUH, Ng Teng Fong General Hospital and Alexandra Hospital), Tan Tock Seng Hospital, Changi General Hospital, Thomson Medical Centre, and several private hospitals operated by Parkway Hospitals Singapore.
The team is looking to swiftly refine the DART based on the feedback provided by different medical departments, and hopes to provide the device as a form of medical aid to Singapore hospitals as well as hospitals in the region. The team will be partnering Temasek Foundation to distribute the DART, complementing its donation of ventilators to the region.
The DART is one of the innovations developed by NUS and NUH to tackle pressing issues that healthcare workers face in the current global pandemic.
Since the start of the crisis, NUS has been proactively participating in the fight against COVID-19 on different fronts, with research ranging from rapid diagnostics to case connections and vaccine development, as well as harnessing information and technology solutions to explore everything from modelling public health to fighting false rumours online. NUH has also been on the front line of the battle against COVID-19, as a tertiary hospital that has treated more than 900 COVID-19 patients to date.
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