Effect of High vs Lose Dosage of Chloroquine Diphosphate on SARS-CoV-2 Infection

JAMA Network Open

EMBARGOED FOR RELEASE: 11:05 A.M. (ET), FRIDAY, APRIL 24, 2020

Media advisory: The full study and editorial linked to this news release.

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What The Study Did: This randomized clinical trial evaluates the safety and efficacy of two  chloroquine diphosphate dosages in patients with severe coronavirus disease 2019 (COVID-19).

Authors: Marcus Vinícius Guimarães Lacerda, M.D., of the Fundação de Medicina Tropical Dr Heitor Vieira Dourado in Manaus, Brazil, is the corresponding author.

(doi:10.1001/jamanetworkopen.2020.8857)

Editor’s Note: The article contains conflict of interest and funding/support disclosures. Please see the article for additional information, including other authors, author contributions and affiliations, conflicts of interest and financial disclosures, and funding and support.

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