Antimicrobial stewardship and drug resistance

21st Century Challenges in Antimicrobial Therapy and Stewardship

addresses selected topics that are of importance in the practice of infectious disease management. The text starts by illustrating the global landscape of antimicrobial drug resistance, which influences antimicrobial use and therapeutic decisions in the clinic. The contributors explain the reasons for the spread of antibiotic resistance, the pharmacology of antibiotics of different classes, innovative drug delivery methods which can improve the efficacy and safety of new drug candidates and achieve targeted drug delivery as well as drug resistance monitoring techniques and issues in the practice of antimicrobial stewardship and infection control.

Key Features:

• 14 organized chapters on several aspects of antimicrobial therapy and stewardship
• Introductory knowledge on global antimicrobial trends
• Coverage of molecular basis of antimicrobial resistance in gram positive, gram negative and fungal microbes
• Focused coverage on new developments in antimicrobial drug development, drug delivery, formulation and diagnostic tools
• Information on unmet needs of patients and clinicians, including the treatment of difficult infections
• Comprehensive coverage of issues in antimicrobial stewardship

21st Century Challenges in Antimicrobial Therapy and Stewardship

brings to readers – healthcare administrators, educators, pharmacists, clinicians and students, alike – the knowledge of the molecular basis of antimicrobial drug therapy, drug resistance in pathogens and current practices in antimicrobial stewardship programs. This knowledge, in turn, fosters an awareness among healthcare industry participants to collaborate in an interprofessional environment to combat multidrug resistance.

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About the Editor:

Michael J. Cawley, PharmD, RRT, CPFT, FCCM, is a professor of clinical pharmacy at the Philadelphia College of Pharmacy, University of the Sciences in Philadelphia, PA (USA). He received his degrees of Bachelor of Science and Doctor of Pharmacy degrees from the Philadelphia College of Pharmacy and Science. He completed a post-doctorate residency in surgical critical care pharmacotherapy at the Philadelphia College of Pharmacy and Science in association with the hospital of the University of Pennsylvania. Dr. Cawley has more than 100 scholarly publications focused on the area of critical care and infectious disease pharmacotherapeutics. He is also recognized as a fellow in the American College of Critical Care Medicine. He served on the editorial boards of several biomedical journals including Annals of Pharmacotherapy (Critical Care Editorial Section), Journal of Respiratory Medicine and Lung Disease and reviewer for Critical Care Medicine, Pharmacotherapy, Journal of Asthma, Clinical Therapeutics, and European Respiratory Journal. Dr. Cawley has been an invited national speaker, presenting more than 230 programs for national and international audiences and served in various roles as an advisory board member and a speaker’s bureau representative for the pharmaceutical industry.

Islam M. Ghazi, PharmD, MSc, BCPS, BCACP, BCIDP, FCPP is a professor, researcher, and specialist practitioner of infectious diseases. He is a graduate of the University of Florida, fellow of Hartford Hospital Center of Anti-infective Research and Development, and assistant professor at Philadelphia College of Pharmacy. In addition to providing pharmaceutical patient care in the domains of ICU, internal medicine, and infectious diseases, Dr. Ghazi has accumulated diverse experience through participation in academic activity including designing and lecturing infectious diseases courses to the pharmacy and medical students and in research activity including the design and execution of research projects related to drug discovery and development ranging from preclinical trials on animals and in vitro in addition to different phases of clinical trials. Dr. Ghazi has authored a variety of peer-reviewed articles, book chapters, and international conference presentations. He has also contributed as an editor and reviewer in several scientific journals. Serving in multiple roles enabled Dr. Ghazi to develop an integrated approach and deep understanding of infectious diseases that he hopes to pass on to the readership.

Keywords:


antimicrobial drug therapy, drug resistance, multidrug resistance, antimicrobial stewardship, infection control, diagnostic tools, infectious disease management

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