Airway Smooth Muscle Clock May Be a Target for Treating Preemies

Article title: Cellular clocks in hyperoxia effects on [Ca2+]i regulation in developing human airway smooth muscle

Authors: Colleen M. Bartman, Aleksey Matveyenko, Christina M. Pabelick, Y. S. Prakash

From the authors: “These data reveal a functional [fetal airway smooth muscle] clock that modulates [intracellular calcium] regulation, particularly in hyperoxia. Harnessing clock biology may be a novel therapeutic consideration for neonatal airway diseases following prematurity.” 

This study is highlighted as one of March’s “best of the best” as part of the American Physiological Society’s APSselect program.