Association between treatment with corticosteroids, risk of death among critically ill patients with COVID-19

What The Study Did:

The results of seven randomized clinical trials with 1,703 critically ill patients with COVID-19 were combined to estimate the association between administration of corticosteroids compared with usual care or placebo and the risk of death after 28 days.

Authors:

Jonathan A.C. Sterne, M.A., M.Sc., Ph.D., of the University of Bristol in England, is the corresponding author.

To access the embargoed study:

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(doi:10.1001/jama.2020.17023)

Editor’s Note:

The article includes conflicts of interest and funding/support disclosures. Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

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Media advisory:

The full study and editorial are linked to this news release. This study is being published to coincide with the release of guidelines from the World Health Organization regarding use of corticosteroids for treatment of critically ill COVID-19 patients.

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