Article title: Elevated FiO2 increases SARS-CoV-2 co-receptor expression in respiratory tract epithelium
Authors: Despoina Myti, Miša Gunjak, Francisco Casado, Solmaz Khaghani Raziabad, Claudio Nardiello, István Vadász, Susanne Herold, Gloria Pryhuber, Werner Seeger, Rory E. Morty
From the authors: “The data presented here document that elevated [fraction of inspired oxygen] increased expression of TMPRSS2 and TMPRSS11D, which are required for efficient viral entry of SARS-CoV-2.”
This study is highlighted as one of November’s “best of the best” as part of the American Physiological Society’s APSselect program.
