Article title: Calcium released by osteoclastic resorption stimulates autocrine/paracrine activities in local osteogenic cells to promote coupled bone formation
Authors: Abu Shufian Ishtiaq Ahmed, Matilda H. C. Sheng, Kin-Hing William Lau, Sean M. Wilson, Daniel Wongwarawat, Xiaolei Tang, Mahdis Ghahramanpouri, Antoine Nehme, Yi Xu, Amir Abdipour, Xiao-Bing Zhang, Samiksha Wasnik, David J. Baylink
From the authors: “In conclusion, our data, together with published data, strongly support the conclusion that calcium signaling plays a vital role in regulating coupled bone formation. The complete mechanistic pathway involved in calcium-regulated coupled bone formation is an important future goal.”
This study is highlighted as one of June’s “best of the best” as part of the American Physiological Society’s APSselect program.
