Article title: Downregulation of the Ca2+-activated K+ channel KCa3.1 in mouse preosteoblast cells treated with vitamin D receptor agonist
Authors: Hiroaki Kito, Haruka Morihiro, Yuka Sakakibara, Kyoko Endo, Junko Kajikuri, Takayoshi Suzuki, Susumu Ohya
From the authors: “Our results showed that decreased expression of the intermediate-conductance Ca2+-activated K+ channel KCa3.1 is one of the key events in the suppression of osteoblastic cell proliferation rate by treatment with a [vitamin D receptor] agonist.”
This study is highlighted as one of August’s “best of the best” as part of the American Physiological Society’s APSselect program.
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