Article title: pH dependence of the Slc4a11-mediated H+ conductance is influenced by intracellular lysine residues and modified by disease-linked mutations
Authors: Bianca N. Quade, Aniko Marshall, Mark D. Parker
From the authors: “Our study has suggested a mechanism by which some mutations can result in loss of function, raises some considerations for personalization of therapeutic intervention and increases our understanding of the structure-function relationships in this unusual Slc4 protein.”
This study is highlighted as one of August’s “best of the best” as part of the American Physiological Society’s APSselect program.
Original post https://alertarticles.info
