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Study Explores Contribution of Calcium, Sodium Inward Currents to Human Motor Activity

Article title: Estimation of self-sustained activity produced by persistent inward currents using firing rate profiles of multiple motor units in humans

Authors: Babak Afsharipour, Nagib Manzur, Jennifer Duchcherer, Keith F. Fenrich, Christopher K. Thompson, Francesco Negro, Katharina A. Quinlan, David J. Bennett, Monica A. Gorassini

From the authors: “A new method of estimating synaptic drive to multiple, simultaneously recorded motor units provides evidence that the portion of the depolarizing drive from persistent inward currents that contributes to self-sustained firing is similar across motoneurons of different sizes.” 

This study is highlighted as one of August’s “best of the best” as part of the American Physiological Society’s APSselect program.

Original post https://alertarticles.info