I’d like to share some groundbreaking news, announced today at the American Association of Cancer Research meeting, that adding a new vaccine type to leading immunotherapy treatment may dramatically reduce melanoma recurrence.
Currently, immunotherapy for melanoma works in patients about half the time, but now, researchers from leading cancer institutions, including the John Theurer Cancer Center, have shown that using a new mRNA vaccine, can significantly reduce the likelihood of melanoma recurring or causing death by 44%, when compared to immunotherapy alone.
Immunotherapies have become the mainstay for treating melanoma, but some patients can become resistant to it. For this reason, researchers looked at adding the mRNA vaccines, the same vaccine used to treat COVID-19 and many other infections, because it can be tailored to target proteins involved in cancer.
Melanoma is the most serious type of skin cancer. In 2023, nearly 187,000 Americans are expected to be diagnosed with the disease. Of these, more than 97,600 will be diagnosed with invasive (Stage I, II, III or IV) melanoma.
The mRNA cancer vaccine is important because it teaches the body’s immune system to recognize virus cells, or in this instance cancer cells, as different and fight them off. These vaccines can be personalized for each patient to target the specific cancer cells in their body. Researchers hope to one day apply this breakthrough to other forms of cancer.
Dr. Andrew Pecora, at the John Theurer Cancer Center campus, (part of Hackensack Meridian Health) in Hackensack New Jersey, worked collaboratively with other investigators on this and is available to speak about this to the media today. JTCC will also be part of the clinical III trials for this study. I’m happy to arrange a time for you to interview Dr. Pecora.
The John Theurer Cancer Center is participating in the phase III clinical trials as part of our ongoing research.
For more information or an interview, contact mary.mcgeever@hmhn.org.
