Understanding SARS-COV-2 proteins is key to improve therapeutic options for COVID-19

COVID-19 has had a significant impact since the pandemic was declared by WHO in 2020, with over 3 million deaths and counting, Researchers and medical teams have been hard at work at developing strategies to control the spread of the infection, caused by SARS-COV-2 virus and treat affected patients.

Biopreparedness Expert Gustavo Palacios, PhD, to Join Mount Sinai, Strengthening Research Collaborations with Department of Defense

Virologist Gustavo Palacios, PhD, is joining the Icahn School of Medicine at Mount Sinai from the United States Army Medical Research Institute of Infectious Diseases (USAMRIID), where he led the application and development of molecular epidemiology to advance the field of biopreparedness. Dr. Palacios will strengthen existing research collaborations between Icahn Mount Sinai and the United States Army-Department of Defense (DoD), laying a foundation for joint research initiatives to protect national and global public health.

Emergency physicians first to safely treat vaccine-induced blood clot with heparin alternative

WASHINGTON, DC — A new case report, detailed in Annals of Emergency Medicine , is the first known case of a patient with VITT (vaccine-induced thrombotic thrombocytopenia) treated with a heparin alternative following the Centers for Disease Control and Prevention…

UNC Charlotte researchers analyzed the host origins of SARS-CoV-2 and other coronaviruses

Coronavirus (CoVs) infection in animals and humans is not new. The earliest papers in the scientific literature of coronavirus infection date to 1966. However, prior to SARS-CoV, MERS-CoV, and SARS-CoV-2, very little attention had been paid to coronaviruses. Suddenly, coronaviruses…

Intranasal influenza vaccine enhances immune response and offers broad protection, researchers find

ATLANTA–An influenza vaccine that is made of nanoparticles and administered through the nose enhances the body’s immune response to influenza virus infection and offers broad protection against different viral strains, according to researchers in the Institute for Biomedical Sciences at…

How a SARS-CoV-2 variant sacrifices tight binding for antibody evasion

The highly infectious SARS-CoV-2 variant that recently emerged in South Africa, known as B.1.351, has scientists wondering how existing COVID-19 vaccines and therapies can be improved to ensure strong protection. Now, researchers reporting in ACS’ Journal of Medicinal Chemistry have…

Sweat sensor could alert doctors, patients to looming COVID cytokine storm (video)

WASHINGTON, April 16, 2021 — Early in the COVID-19 pandemic, doctors recognized that patients who developed a “cytokine storm” — a surge of pro-inflammatory immune proteins — were often the sickest and at highest risk of dying. But a cytokine…

Why SARS-CoV-2 replicates better in the upper respiratory tract

“SARS-CoV-2 and SARS-CoV are highly similar genetically, generate a homologous repertoire of viral proteins, and use the same receptor to infect human cells. However, despite these similarities, there are also important differences between the two viruses”, says Ronald Dijkman from…

Analysis of the sensitivity of the UK (B.1.1.7) and South African (B.1.351) variants to SARS-CoV-2

The B.1.1.7 and B.1.351 variants of SARS-CoV-2 were first detected in the UK and South Africa respectively, and have since spread to many other countries. Scientists from the Institut Pasteur joined forces with Orléans Regional Hospital, Tours University Hospital, Créteil…