An international team of scientists from the Menzies Health Institute Queensland (MHIQ) at Griffith University and from City of Hope, a research and treatment center for cancer, diabetes and other life-threatening diseases in the U.S., have developed an experimental direct-acting…
Tag: VIROLOGY
How x-rays could make reliable, rapid COVID-19 tests a reality
An imaging technique pioneered by Berkeley Lab is helping reveal the best antibodies for COVID-19 detection
Dental procedures during pandemic are no riskier than a drink of water
A new study’s findings dispel the misconception that patients and providers are at high risk of catching COVID-19 at the dentist’s office.
Understanding SARS-COV-2 proteins is key to improve therapeutic options for COVID-19
COVID-19 has had a significant impact since the pandemic was declared by WHO in 2020, with over 3 million deaths and counting, Researchers and medical teams have been hard at work at developing strategies to control the spread of the infection, caused by SARS-COV-2 virus and treat affected patients.
Scientists develop better way to block viruses that cause childhood respiratory infections
By engineering a short chunk of protein, or peptide, that can prevent the attachment of human parainfluenza viruses to cells, researchers have improved a method in rodent models intended to help keep children healthy.
Biopreparedness Expert Gustavo Palacios, PhD, to Join Mount Sinai, Strengthening Research Collaborations with Department of Defense
Virologist Gustavo Palacios, PhD, is joining the Icahn School of Medicine at Mount Sinai from the United States Army Medical Research Institute of Infectious Diseases (USAMRIID), where he led the application and development of molecular epidemiology to advance the field of biopreparedness. Dr. Palacios will strengthen existing research collaborations between Icahn Mount Sinai and the United States Army-Department of Defense (DoD), laying a foundation for joint research initiatives to protect national and global public health.
Harvard University licenses its nasal swab collection technology to Rhinostics
The combined technologies could reduce labor and time required for COVID-19 diagnostic testing 10-fold, and facilitate future diagnostic testing of other respiratory diseases
Emergency physicians first to safely treat vaccine-induced blood clot with heparin alternative
WASHINGTON, DC — A new case report, detailed in Annals of Emergency Medicine , is the first known case of a patient with VITT (vaccine-induced thrombotic thrombocytopenia) treated with a heparin alternative following the Centers for Disease Control and Prevention…
Surfaces can be designed with antiviral properties to mitigate COVID-19
An optimally designed surface can speed the decay of a viral load
UNC Charlotte researchers analyzed the host origins of SARS-CoV-2 and other coronaviruses
Coronavirus (CoVs) infection in animals and humans is not new. The earliest papers in the scientific literature of coronavirus infection date to 1966. However, prior to SARS-CoV, MERS-CoV, and SARS-CoV-2, very little attention had been paid to coronaviruses. Suddenly, coronaviruses…
Intranasal influenza vaccine enhances immune response and offers broad protection, researchers find
ATLANTA–An influenza vaccine that is made of nanoparticles and administered through the nose enhances the body’s immune response to influenza virus infection and offers broad protection against different viral strains, according to researchers in the Institute for Biomedical Sciences at…
Speeding new treatments
UNM team creates powerful computational tool to help researchers rapidly screen molecules for anti-COVID properties
Human organ chips enable COVID-19 drug repurposing
Emulating the human lung airway in vitro identified the SARS-CoV2-inhibiting effects of the antimalarial drug amodiaquine, which is now in COVID-19 clinical trials
Large collaboration creates cell atlas of COVID-19 pathology
Single-cell analysis of autopsy samples from COVID-19 patients shows how the lungs repeatedly tried, and failed, to repair themselves
Risk factors for a severe course of COVID-19 in people with diabetes
People with diabetes are at increased risk of developing a severe course of COVID-19 compared to people without diabetes. The question to be answered is whether all people with diabetes have an increased risk of severe COVID-19, or whether specific…
How SARS-CoV-2 Hijacks Human Cells to Evade Immune System
UC San Diego School of Medicine researchers discovered one way in which SARS-CoV-2 hijacks human cell machinery to blunt the immune response, allowing it to establish infection, replicate and cause disease.
COVID-19 may result in prolonged infection in immunocompromised children and young adults
Children and young adults with compromised immune systems, such as those undergoing cancer treatment, may experience a prolonged period of infection with SARS-CoV-2, the virus that causes COVID-19, and the extended duration of infection may increase the incidence of mutations.…
How a SARS-CoV-2 variant sacrifices tight binding for antibody evasion
The highly infectious SARS-CoV-2 variant that recently emerged in South Africa, known as B.1.351, has scientists wondering how existing COVID-19 vaccines and therapies can be improved to ensure strong protection. Now, researchers reporting in ACS’ Journal of Medicinal Chemistry have…
Five new insights in the fight against COVID-19
Researchers announce new findings on treatments, health impacts and repercussions for science education
Researchers design sensor for fast, inexpensive on-site Ebola detection
Sensor technology requires no special storage; could also be useful for detecting COVID-19
Study illuminates how COVID-19 worms its way into the brain
Research helps explain baffling neurological symptoms — and why they’re so unpredictable
SARS-CoV-2 spike protein alone may cause lung damage
New mouse model makes it easier and safer to study COVID-19 lung injury
Benefits of AstraZeneca COVID-19 vaccine outweigh its risks
Pausing AstraZeneca vaccinations because of suspected links to deadly blood clots could allow COVID-19 to continue to spread, cause more deaths.
An atlas of HIV’s favorite targets in the blood of infected individuals
Gladstone researchers have identified the blood cells most likely to be targeted by HIV during a real-life infection
Cleveland Clinic, Case Western Reserve University find COVID-19 variants may offer clues in predicting patient outcomes as virus evolves
Researchers collaborate on genetic study of SARS-CoV-2 mutations
Faster Air Exchange in Buildings Not Always Beneficial for Coronavirus Levels
Modeling study suggests vigorous ventilation can cause spike in viral concentrations
Updated results on coronavirus vaccination effectiveness
Clalit Research Institute publishes updated results on coronavirus vaccination effectiveness in the New England Journal of Medicine
Certain gut microbes make mosquitoes more prone to carry malaria parasite
Dietary sugars and gut microbes play a key role in promoting malaria parasite infection in mosquitoes. Researchers in China have uncovered evidence that mosquitoes fed a sugar diet show an increased abundance of the bacterial species Asaia bogorensis, which enhances…
SARS-CoV-2 variants from mink evade inhibition by antibodies
It has been known for about a year that minks can become infected with SARS-CoV-2. The virus had been transmitted from humans to farmed mink and mutated in infected animals. Mutations were acquired in the spike protein, which is crucial…
Sweat sensor could alert doctors, patients to looming COVID cytokine storm (video)
WASHINGTON, April 16, 2021 — Early in the COVID-19 pandemic, doctors recognized that patients who developed a “cytokine storm” — a surge of pro-inflammatory immune proteins — were often the sickest and at highest risk of dying. But a cytokine…
Significant spread of all coronavirus variants tracked in Houston area
Study underscores the need for greatly increased genome surveillance to rapidly identify and track the emergence and introduction of SARS-CoV-2 variants in the United States, investigators report in The American Journal of Pathology
Combining mask wearing, social distancing suppresses COVID-19 virus spread
Network model findings could shape public health policy for airborne viruses
The incredible bacterial ‘homing missiles’ that scientists want to harness
A Berkeley Lab-led team is digging into the bizarre bacteria-produced nanomachines that could fast-track microbiome science
The future of biodiversity collections
Events such as the COVID-19 pandemic have highlighted the crucial role played by biodiversity collections in enabling rapid responses to crises and in facilitating ongoing research across numerous fields. Despite the recognized value of this infrastructure, the community nevertheless has…
Ultrasensitive, rapid diagnostic detects Ebola earlier than gold standard test
Portable platform detects early biomarkers of the Ebola virus faster than PCR, the current industry standard
Deep dive into key COVID-19 protein is a step toward new drugs, vaccines
Researchers in the Oregon State University College of Science have taken a key step toward new drugs and vaccines for combating COVID-19 with a deep dive into one protein’s interactions with SARS-CoV-2 genetic material.
Experimental Therapy for Parasitic Heart Disease May Also Help Stop COVID-19
UC San Diego researchers found that the chemical inhibitor K777 reduces the coronavirus’ ability to infect cell lines by blocking human enzyme cathepsin L; clinical trials are underway.
Massive X-ray screening identifies promising candidates for COVID drugs
DESY’s X-ray lightsource PETRA III reveals existing active substances binding to key virus protein
B.1.1.7 variant of COVID-19 spreading rapidly in United States
A genetic analysis of virus samples suggests that the UK-originating variant, which is 40-50 percent more transmissible, entered the country in late November 2020
Why SARS-CoV-2 replicates better in the upper respiratory tract
“SARS-CoV-2 and SARS-CoV are highly similar genetically, generate a homologous repertoire of viral proteins, and use the same receptor to infect human cells. However, despite these similarities, there are also important differences between the two viruses”, says Ronald Dijkman from…
Temperature sensor could help safeguard mRNA vaccines
Scientists have developed vaccines for COVID-19 with record speed. The first two vaccines widely distributed in the U.S. are mRNA-based and require ultracold storage (-70 C for one and -20 C for the other). Now, researchers reporting in ACS Omega…
Getting to the core of HIV replication
HIV-1 viral capsid simulations on XSEDE-allocated Stampede2, Bridges, Darwin systems uncover nucleotide entry mechanism
Herpesvirus triggers cervical cancer affecting nearly 1 in 4 adult sea lions
Sea lions are critical model for understanding how cancer develops, parallels to human cancer research
Anti-inflammatory drug protects against lethal inflammation from COVID-19 in animal models
Mount Sinai researchers have found that a widely available and inexpensive drug targeting inflammatory genes has reduced morbidity and mortality in mice infected with SARS-CoV-2, the virus that causes COVID-19. In a study published today in the journal Cell ,…
Viewing the virus close up
Technology project with Heidelberg participation wants to develop compact cell-imaging for extensive application
Everyone poops: Monitoring COVID-19 in wastewater
University of Missouri scientists receive $4 million grant from the National Institutes of Health to examine clues about the rate of infection in communities and virus variants
Differences in herpes virus symptoms may relate to variations in strain gene expression
UNIVERSITY PARK, Pa. — Why do some people with cold sores around their lips experience painful lesions, while others have no symptoms at all, yet still spread the virus? A new study conducted at Penn State finds that these differences…
Chronic viral infections can have lasting effects on human immunity, similar to aging
Researchers identify signatures of immune dysfunction that are shared in aging and chronic viral infections of HIV and Hepatitis C
Analysis of the sensitivity of the UK (B.1.1.7) and South African (B.1.351) variants to SARS-CoV-2
The B.1.1.7 and B.1.351 variants of SARS-CoV-2 were first detected in the UK and South Africa respectively, and have since spread to many other countries. Scientists from the Institut Pasteur joined forces with Orléans Regional Hospital, Tours University Hospital, Créteil…
COVID-19: A retrospective by the numbers
Godot is in sight