Experts in the field of immunotherapy will gather virtually on June 18, 2021
Tag: VIROLOGY
NIH researchers identify potential new antiviral drug for COVID-19
Compound targets essential viral enzyme and prevents replication in cells
Pfizer-BioNTech vaccine recipients have lower antibody levels targeting the Delta variant
Levels of antibodies in the blood of vaccinated people that are able to recognise and fight the new SARS-CoV-2 Delta variant first discovered in India (B.1.617.2) are on average lower than those against previously circulating variants in the UK, according…
The dream team: Scientists find drug duo that may cure COVID-19 together
Preclinical experiments show that the drugs cepharanthine and nelfinavir may be effective treatments for COVID-19
Study offers insights for communicating about wildlife, zoonotic disease amid COVID-19
A new study from North Carolina State University found that certain types of messages could influence how people perceive information about the spread of diseases from wildlife to humans. The researchers say the findings, published in the journal Frontiers in…
Electronic nose might “sniff out” COVID-19-infected people at mass scale
Electronic nose might “sniff out” COVID-19-infected people at mass scale, according to a preliminary proof-of-concept study
Male piglets less resilient to stress when moms get sick during pregnancy
URBANA, Ill. -When pigs get hit with significant illnesses during key stages of pregnancy, their immune response may negatively affect developing piglets, making them less productive on the farm. New research from the University of Illinois shows that when those…
How HIV infection shrinks the brain’s white matter
Researchers from Penn and CHOP detail the mechanism by which HIV infection blocks the maturation process of brain cells that produce myelin, a fatty substance that insulates neurons
Future Pandemic? Consider Radically Altering Animal Agriculture Practices
FAU Bioethicist Offers Plausible Solutions to Mitigate Zoonotic Risk from Agriculture and Food Production for Public Health
At-home COVID-19 tests: How good are they?
As the country gets vaccinated and begins to re-open, testing remains a key element of safe interactions. Rapid testing for COVID-19 has become more common and accessible, including over-the-counter (OTC) tests approved by the U.S. Food and Drug Administration (FDA).…
Researchers make first-ever discovery of Zika virus RNA in free-ranging African bats
A team of Colorado State University scientists, led by veterinary postdoctoral fellow Dr. Anna Fagre, has detected Zika virus RNA in free-ranging African bats. RNA, or ribonucleic acid, is a molecule that plays a central role in the function of…
Direct action of SARS-CoV-2 on organs may cause exacerbated immune response in children
Researchers found that SARS-CoV-2 had spread throughout the body via the blood vessels, infecting various types of cell and tissue in these children; the clinical manifestations varied according to the organ targeted
Analysis reveals global ‘hot spots’ where new coronaviruses may emerge
Forest fragmentation, agricultural expansion and concentrated livestock production in China and Southeast Asia are bringing humans into closer contact with bats known to carry zoonotic diseases
How retroviruses become infectious
Scientists at IST Austria discover how the HIV-related Rous sarcoma virus is assembled driving virus research forward.
Prognostic value of troponin I in COVID-19 patients
This article by Dr. Alaa A. Ghaleb and colleagues is published in The Open Cardiovascular Medicine Journal, 2021
FAPESP will discuss an integrative approach to clinical long-term effects of COVID-19
Renowned scientists sharing their research and clinical practice will take part at the webinar. They will tackle the patients’ evolving clinical conditions and the challenges of dealing with the subacute phase.
Watch me move it, move it: Gliding structure in Mycoplasma mobile revealed
Researchers detect internal motor structure of Mycoplasma mobile using high-speed atomic force microscopy
Climate change makes West Nile virus outbreaks ‘plausible’ in UK
Risk of mosquito-borne pathogen spreading to the country will increase as temperatures rise, say scientists
DNA vaccines for COVID-19 effective in mice, hamsters
Currently available COVID-19 vaccines rely on mRNA strands to teach the human immune system to recognize the SARS-CoV-2 virus. Now, researchers reporting in PLOS Neglected Tropical Diseases have reported the successful development of a vaccine that instead uses DNA encoding…
Versatile coronavirus antibody may be starting point for broader-acting vaccines
A special type of antibody is produced in patients who’ve had COVID-19 as well as less-serious coronaviruses that cause colds.
A comprehensive profile of California’s ‘homegrown’ coronavirus
New analysis suggests the California variant is more transmissible than unmutated strains, but vaccines are effective against it
Novel sensor discovered that helps bacteria detect and respond to formaldehyde
The EfgA protein directly senses elevated levels of formaldehyde and stops growth to protect cells
Salmon virus originally from the Atlantic, spread to wild Pacific salmon from farms: Study
Study finds Piscine orthoreovirus (PRV) is now almost ubiquitous in salmon farms in British Columbia, Canada.
Ultra-low doses of inhaled nanobodies effective against COVID-19 in hamsters
PITTSBURGH, May 26, 2021 – In a paper published today in Science Advances , researchers from the University of Pittsburgh School of Medicine showed that inhalable nanobodies targeting the spike protein of the SARS-CoV-2 coronavirus can prevent and treat severe…
Coronavirus testing made quick and easy
A new rapid coronavirus test developed by KAUST scientists can deliver highly accurate results in less than 15 minutes. The diagnostic, which brings together electrochemical biosensors with engineered protein constructs, allows clinicians to quickly detect bits of the virus with…
Hundreds of antibiotic resistant genes found in the gastrointestinal tracts of Danish infants
Danish one-year-olds carry several hundred antibiotic resistant genes in their bacterial gut flora according to a new study from the University of Copenhagen. The presence of these genes is partly attributable to antibiotic use among mothers during pregna
Research uncovers how ‘non-professional’ cells can trigger immune response
Worm cells sense changes in metabolism to activate defensive measures against pathogens
Conquering COVID-19 with antivirals
The COVID-19 pandemic has seen scientists perform incredible feats in a short amount of time, from developing tests to new types of vaccines. Despite these victories, experts are still working to develop an effective antiviral drug to kill the SARS-CoV-2…
Harnessing next generation sequencing to detect SARS-CoV-2
…and prepare for the next pandemic
SARS-CoV-2: Estimating infectiousness
Science publishes new study on viral load
A COVID-fighter’s guide to T cells
New LJI review shows how T cells target more than 1,400 sites on SARS-CoV-2
SARS-CoV-2 RNA discovery unlocks new potential treatments
An international and multidisciplinary team led by researchers at the University of Oxford, University of Glasgow, and University of Heidelberg, has uncovered the interactions that SARS-CoV-2 RNA establishes with the host cell, many of which are fundamental for infection. These…
Virus infection cycle revealed in dynamic detail
A critical process in the infection cycle of viruses has been revealed for the first time in dynamic detail using pioneering plant-based technology. Evidence about the process of virus maturation revealed in the research could help us develop new methods…
How hepatitis C virus evades the immune system
Researchers from Osaka University discover a novel molecular mechanism by which hepatitis C virus evades the immune system to cause chronic infection
Flu fighter: Nanoparticle-based vaccine effective in preclinical trials
The vaccine, made of disease-fighting proteins, could boost efficacy, accelerate production of seasonal flu vaccines
A novel defense mechanism for SARS-CoV-2 discovered
Scientists from Hokkaido University have discovered a novel defensive response to SARS-CoV-2 that involves the viral pattern recognition receptor RIG-I. Upregulating expression of this protein could strengthen the immune response in COPD patients. In the 18 months since the first…
Newly identified antibody can be targeted by HIV vaccines
The previously undescribed antibody points to new vaccine strategies for HIV, COVID
Coronavirus transmission in Queens drove the first wave of New York city’s pandemic
The most populous boroughs in New York City, Queens and Brooklyn, likely served as the major hub of COVID-19 spread in the spring of 2020, a new study finds. Led by researchers at NYU Grossman School of Medicine, the new…
A brand new cocktail to fight HIV
Montréal, May 20, 2021–Researchers at the University of Montreal Hospital Research Centre (CRCHUM) and Yale University have succeeded in reducing the size of the HIV reservoir in humanized mice by using a “molecular can opener” and a combination of antibodies…
Sheltering people with COVID-19 experiencing homelessness curbs spread
A new study provides public health planning authorities with a method of calculating the number of COVID-19 isolation beds they would need for people experiencing homelessness based on level of infection in the city. The research holds promise for controlling…
Immune genetics and previous common cold infections might help protect Japan from COVID-19
A highly immunogenic HLA-A*24:02-restricted T cell epitope is shared between COVID-19 and common cold coronaviruses
Emerging H5N8 avian influenza viruses are a serious public health concern
The emergence and global spread of the highly pathogenic H5N8 avian influenza virus (AIV), a pathogen that has caused continuous and ongoing outbreaks with massive mortality in both wild and farmed birds across Eurasia and Africa throughout 2020, represents a…
Insect and animal invasions can teach us about COVID-19
Invasions by alien insect and animal species have much in common with outbreaks of infectious diseases and could tell us a great deal about how pandemics spread, according to a research paper published today.
Modeling can predict mutation “hotspots” and antibody escapers in SARS-CoV-2 spike protein
Study identifies structural basis of spike protein mutations with stronger binding and antibody resistance, which may explain transmissibility of new COVID-19 variants
A new rapid test detects a coronavirus infection in 10 minutes
An antigen-based detection technique developed by University of Helsinki researchers could be used to analyze as many as 500 samples per hour
A rapid antigen test for SARS-CoV-2 in saliva
Scientists from Hokkaido University have shown that an antigen-based test for quantifying SARS-CoV-2 in saliva samples is simple, rapid, and more conducive for mass-screening. More than a year into the COVID-19 pandemic, the RT-PCR test remains the gold standard for…
City of Hope and Griffith University develop direct-acting antiviral to treat COVID-19
An international team of scientists from the Menzies Health Institute Queensland (MHIQ) at Griffith University and from City of Hope, a research and treatment center for cancer, diabetes and other life-threatening diseases in the U.S., have developed an experimental direct-acting…
How x-rays could make reliable, rapid COVID-19 tests a reality
An imaging technique pioneered by Berkeley Lab is helping reveal the best antibodies for COVID-19 detection
Adding antibodies to enhance photodynamic therapy for viral and bacterial disease
Advancing PDT as a rapid response to pandemics
COVID-19 testing method gives results within one second
Superfast, portable COVID-19 testing method detects the virus much faster than currently available methods