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UrduMeningitis is associated with high mortality and frequently causes severe sequelae. Newborn infants are particularly susceptible to this type of infection; they develop meningitis 30 times more often than the general population. Group B streptococcus (GBS) bacteria are the most…
Tag: VIROLOGY
Sensitivity of the Delta variant to sera from convalescent and vaccinated individuals
COVID-19: analysis of the sensitivity of the Delta variant to monoclonal antibodies and sera from convalescent and vaccinated individuals
Why we need to talk openly about vaccine side effects
We need to talk openly about vaccine side effects if we are to defeat the coronavirus pandemic
Stem cells can use same method as plants and insects to protect against viruses
Researchers at the Francis Crick Institute have found a vital mechanism, previously thought to have disappeared as mammals evolved, that helps protect mammalian stem cells from RNA viruses such as SARS-CoV-2 and Zika virus. The scientists suggest this could one…
Anti-coagulant drug could treat COVID-19’s emerging variants
New targetable site on the COVID-19 spike protein discovered
Mount Sinai research reveals how Ebola virus manages to evade the body’s immune defenses
New York, NY (July 6, 2021) – Mount Sinai researchers have uncovered the complex cellular mechanisms of Ebola virus, which could help explain its severe toll on humans and identify potential pathways to treatment and prevention. In a study published…
New cancer findings can give wider access to immunotherapy
Researchers at Karolinska Institutet in Sweden publish new findings in the journal Cancer Discovery showing how pharmacological activation of the protein p53 boosts the immune response against tumours. The results can be of significance to the development of new combination…
Epsilon variant mutations contribute to COVID immune evasion
Studies reveal unprecedented mechanism behind loss of antibody neutralization against this pandemic coronavirus variant of concern
Inside the lungs, a new hope for protection against flu damage
New experimental data pinpoints a molecular component responsible for modulating the damage the flu can wreck on the lungs
Kansas State University virologists publish new findings on SARS-CoV-2 treatment option
MANHATTAN, KANSAS — A recent study by Kansas State University virologists demonstrates successful postinfection treatment for SARS-CoV-2, the virus that causes COVID-19. College of Veterinary Medicine researchers Yunjeong Kim and Kyeong-Ok “KC” Chang published the study in the prestigious journal…
Chasing the cells that predict death from severe COVID-19
Gladstone scientists have uncovered T-cell signatures that may help understand why some people succumb to severe COVID-19 while others recover
SARS-CoV-2 replication targets nasal ciliated cells early in COVID-19 infection
The establishment of nasal mucosal immunity against SARS-CoV-2 through a nasal vaccine could be the most efficient way to combat COVID-19 infection
Mefloquine: A promising drug ‘soldier’ in the battle against COVID-19
Scientists propose the repurposing of anti-malarial drug mefloquine to fight the novel coronavirus
Cutting out the proteins that give SARS-CoV-2 its power
Researchers at Texas Biomedical Research Institute (Texas Biomed) have narrowed down the proteins enabling SARS-CoV-2 to cause disease. Using advanced genetic engineering techniques developed at Texas Biomed, they systematically deleted the genetic code for five of the virus’s accessory proteins, one at a time, to see how each one affected the virus’s ability to spread and cause illness. The research was published online this month in the Journal of Virology.
Study finds structural changes in the SARS-CoV-2 Alpha and Beta variants
Changes to the ‘spike’ protein explain Alpha’s faster spread, and how the Beta variant evades immune responses, suggesting the need for a booster with an updated vaccine
Higher doses of neutralizing antibody could protect humans against HIV
Although the Antibody Mediated Prevention (AMP) study that launched in 2016 failed to show significant efficacy in a pair of clinical trials, Denis Burton argues in a Perspective that the AMP study’s results represent a landmark in AIDS research; they…
Had COVID-19? One vaccine dose enough; boosters for all, study says
Two mRNA vaccines against COVID-19 have proven safe and effective in clinical trials, as well as in the millions of people who have been vaccinated so far. But how prior SARS-CoV-2 infection affects vaccine response, and how long that response…
Sneeze cam reveals best fabric combos for cloth masks (video)
During the COVID-19 pandemic, cloth face masks became a way to help protect yourself and others from the virus. And for some people, they became a fashion statement, with many fabric choices available. But just how effective are they, especially…
Engineering nanobodies as lifesavers when SARS-CoV-2 variants attack
Scientists are pursuing a new strategy in the protracted fight against the SARS-CoV-2 virus by engineering nanobodies that can neutralize virus variants in two different ways.
A tapeworm drug against SARS-CoV-2?
Charité conducts clinical trial to test potential new treatment
The paths through which COVID-19 spread across Brazil
The impact of super-spreader cities, highways, and intensive care availability in the early stages of the COVID-19 epidemic in Brazil
Researchers explore microbial ecosystem in search of drugs to fight SARS-CoV-2
Washington, DC – June 20, 2021 – Researchers from Yonsei University in South Korea have found that certain commensal bacteria that reside in the human intestine produce compounds that inhibit SARS-CoV-2. The research will be presented on June 20 at…
Study evaluates potential causes of increased transmission in SARS-CoV-2 variants
Patients with B.1.1.7 and B.1.351 less likely to be asymptomatic, despite no increase in viral load
Vaccination, previous infection, protect against COVID-19 gamma/P.1 variant in animal model
In a new study using variant virus recovered from one of the original travelers, researchers in the U.S. and Japan have found that vaccination with an mRNA vaccine induces antibody responses that would protect humans from infection with the gamma/P.1 variant.
Coronaviruses may achieve their pathogenic edge by triggering programmed cell death
Targeting highly pathogenic coronavirus-induced apoptosis reduces viral pathogenesis and disease severity
Longer duration of positive COVID-19 PCR test results in people with certain comorbidities
Boston – New study results indicate that different comorbid conditions affecting individuals diagnosed with COVID-19 may impact how long they continue to receive positive SARS-CoV-2 polymerase chain reaction (PCR) test results. Individuals diagnosed with COVID-19 who are aged 60+, have…
Southwest National Primate Research Center at Texas Biomed receives $37 million NIH grant
The Southwest National Primate Research Center (SNPRC) at Texas Biomed has been awarded more than $37 million from the National Institutes of Health to continue operations into 2026. The P51 grant, given by the NIH Office of Research Infrastructure Programs, provides essential funding to house and care for nearly 2,500 non-human primates that are part of life-science research programs at Texas Biomed and partners around the globe.
Accomplished University of Ottawa professors earn Canada Research Chairs
The University of Ottawa has been awarded four new Canada Research Chairs
AI Predicts How Patients with Viral Infections, Including COVID-19, Will Fare
UC San Diego School of Medicine researchers discovered gene expression patterns associated with pandemic viral infections, providing a map to help define patients’ immune responses, measure disease severity, predict outcomes and test therapies — for current and future pandemics.
Changing community networks impact disease spread
The COVID-19 pandemic has made clear the importance of understanding precisely how diseases spread throughout networks of transportation. However, rigorously determining the connection between disease risk and changing networks–which either humans or the environment may alter–is challenging due to the…
Study identifies how COVID-19 linked to Alzheimer’s disease-like cognitive impairment
Cleveland Clinic-led research team used artificial intelligence to uncover association between COVID-19 and brain changes
A better understanding of ‘wet markets’ is key to safeguarding human health, biodiversity
PRINCETON, N.J.–Great uncertainty surrounds the origins of SARS-CoV-2. Early on, some suggested a link between COVID-19 and a seafood market in Wuhan, China. Other theories are now circulating, though the origins of the virus are still unknown. In response, governments…
Scientists uncover the mysteries of how viruses evolve
Scientists uncover the mysteries of how viruses evolve
SARS-CoV-2 Detectable — Though Likely Not Transmissible — on Hospital Surfaces
UC San Diego School of Medicine researchers discovered that SARS-CoV-2, or at least its genetic signature, abounds on hospital surfaces, often co-locating with one particular type of bacteria.
SARS-CoV-2 protease cuts human proteins; possible link to COVID-19 symptoms
The SARS-CoV-2 papain-like protease (PLpro) plays an essential role in processing viral proteins needed for replication. In addition, the enzyme can cut and inactivate some human proteins important for an immune response. Now, researchers reporting in ACS Infectious Diseases have…
Warmer temperatures lessen COVID-19 spread, but control measures still needed
New research shows transmission of the virus behind COVID-19 varies seasonally, but warmer conditions are not enough to prevent transmission. The study, led by Imperial College London researchers and published today in Proceedings of the National Academy of Sciences ,…
SARS-CoV-2 detectable — though likely not transmissible — on hospital surfaces
The coronavirus that causes COVID-19 also tends to co-locate with one particular type of bacteria
Creating a needle-free COVID-19 vaccine
Vaccines are mostly synonymous with needles, an efficient and effective way to provide immunity to myriad infections. As COVID-19 vaccination efforts roll out across the U.S. and the world, some experts believe that a vaccine administered through the nose could…
How COVID-19 wreaks havoc on human lungs
New structure shows how virus envelope protein hijacks cell-junction protein and promotes viral spread; findings could speed the design of drugs to block severe effects of COVID-19
A vital tool to study virus evolution in the test tube
Variants of viruses, such as that causing COVID-19, can now be quickly studied in the laboratory, even before they emerge in nature and become a major public health challenge. The University of Queensland, QIMR Berghofer Medical Research Institute, Peter Doherty…
Researchers used smart watches to monitor changes in quality of life during lockdowns
Data on 20-40 age group reveals: They sleep more, walk less and feel unhappier
Simple blood test can accurately reveal underlying neurodegeneration
A single biomarker can accurately indicate the presence of underlying neurodegeneration in people with cognitive issues
A mechanism through which ‘good’ viruses kill ‘bad’ bacteria and block their reproduction
An important step in the battle against antibiotic-resistant bacteria
A new hope: A novel vaccine against COVID-19 is safe and induces antibody production
Early-phase clinical trials show that a vaccine called KCONVAC is safe and stimulates antibody production in Chinese adults
Researchers discover how cowpea mosaic plant virus activates immune system against cancer
Immunology researchers led by Dartmouth and Dartmouth-Hitchcock’s Norris Cotton Cancer Center discover how the cowpea mosaic plant virus is recognized by and strongly stimulates the immune system to attack and often eliminate cancerous tumors
SMART researchers develop method for rapid, accurate detection of viruses
Four times faster than conventional PCR methods, new approach called RADICA is highly specific, sensitive, and resistant to inhibitors
A missing antibody molecule may indicate when dengue will become deadly
A first encounter with the dengue virus typically causes very mild symptoms; however, a subsequent infection is a different story. For a small proportion of people who are reinfected, the virus can cause severe symptomatic disease, which is often life-threatening.…
“Mexican variant” and monitoring actions of SARS-CoV-2 genome
A research group of the Department of Pharmacy and Biotechnology of the University of Bologna analyzed more than one million SARS-CoV-2 genome sequences. This analysis led to the identification of a new variant that, over the past weeks, has been…
Curis, Inc. announces ‘VISTA: A new immune checkpoint in cancer, autoimmunity and beyond’
Experts in the field of immunotherapy will gather virtually on June 18, 2021
NIH researchers identify potential new antiviral drug for COVID-19
Compound targets essential viral enzyme and prevents replication in cells