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UrduThe number of COVID-19 variants is growing rapidly, so much that the scale and scope of mutation may pose a threat to the continuing successful use of the current vaccines and therapies. The findings, by an international team that includes University of California researchers, are being published in the June edition of the peer-reviewed journal EMBO Molecular Medicine. The pace of variation of the SARS-CoV-2 virus strains makes plain the threat that rapidly evolving new strains might give rise to escape variants, capable of limiting the efficacy of vaccines, therapies, and diagnostic tests.
Tag: Vaccines
Southwest National Primate Research Center at Texas Biomed receives $37 million NIH grant
The Southwest National Primate Research Center (SNPRC) at Texas Biomed has been awarded more than $37 million from the National Institutes of Health to continue operations into 2026. The P51 grant, given by the NIH Office of Research Infrastructure Programs, provides essential funding to house and care for nearly 2,500 non-human primates that are part of life-science research programs at Texas Biomed and partners around the globe.
COVID-19 reinfection rate less than 1% for those with severe illness
Two deaths were associated with reinfection, but most cases were mild
Study reveals COVID-19 risk factors for those with IDD
Syracuse, N.Y. – A study of nearly 550 adults with intellectual and developmental disabilities receiving residential services in New York City found that age, larger residential settings, Down syndrome and chronic kidney disease were the most common risk factors for…
Women leaving jail have high vaccine hesitancy; app drops resistance, boosts literacy
Vulnerable population offers keys to better communications on vaccines, researchers argue
COVID-19 vaccine hesitancy among patients with breast cancer
What The Study Did: This survey study among women with breast cancer in Mexico evaluates their specific concerns about and high hesitancy rate toward COVID-19 vaccination. Authors: Cynthia Villarreal-Garza, M.D., D.Sc., of the Breast Cancer Center, Hospital Zambrano Hellion TecSalud…
Speech droplets drive transmission of SARS-CoV-2
A new review published in the Journal of Internal Medicine indicates that unmasked speech in confined spaces poses the greatest risk of spreading SARS-CoV-2, the virus that causes COVID-19, to others. The focus of the review is on the interface…
Creating a needle-free COVID-19 vaccine
Vaccines are mostly synonymous with needles, an efficient and effective way to provide immunity to myriad infections. As COVID-19 vaccination efforts roll out across the U.S. and the world, some experts believe that a vaccine administered through the nose could…
Study confirms safety and effectiveness of COVID-19 vaccination in people with cancer
Since the early days of the COVID-19 pandemic, there were questions about how people in active cancer treatment would fare if they became infected with SARS-CoV-2. The worries were due, in large part, to the effects that cancer and its…
COVID vaccine linked to low platelet count, nationwide study suggests
A condition that affects the blood, known as idiopathic thrombocytopenic purpura (ITP), may be associated the Oxford-AstraZeneca vaccine in rare cases, research suggests. The very small increased risk of the condition – which is characterised by low platelet counts –…
UT extension receives grants for COVID-19 and other vaccine education
USDA, CDC and Cooperative Extension team to support communication nationwide
Social media use one of four factors related to higher COVID-19 spread rates early on
TORONTO, June 9, 2021 – Researchers from York University and the University of British Columbia have found social media use to be one of the factors related to the spread of COVID-19 within dozens of countries during the early stages…
MCRI’s BCG vaccine trial joins global race to better understand COVID-19 variants
An Australian-led study will investigate whether it’s possible to predict who remains susceptible to SARS-CoV-2 variants after having COVID-19 or receiving a COVID-19-specific vaccine. The study will explore the immune response to COVID-19-specific vaccines in Brazilian healthcare workers to find…
Vilcek Foundation awards $100,000 prize to Dr. Katalin Karikó for pioneering mRNA research
Dr. Katalin Karikó receives the 2022 Vilcek Prize for Excellence in Biotechnology for her scientific contributions that led to the development of mRNA vaccines for COVID-19
A new hope: A novel vaccine against COVID-19 is safe and induces antibody production
Early-phase clinical trials show that a vaccine called KCONVAC is safe and stimulates antibody production in Chinese adults
Researchers discover how cowpea mosaic plant virus activates immune system against cancer
Immunology researchers led by Dartmouth and Dartmouth-Hitchcock’s Norris Cotton Cancer Center discover how the cowpea mosaic plant virus is recognized by and strongly stimulates the immune system to attack and often eliminate cancerous tumors
Effectiveness of 1st dose of BNT162b2 (BioNTech/Pfizer) vaccine for SARS-CoV-2 infection 13 to 24 days after immunization
What The Study Did: In this study, s hort-term effectiveness of the first dose of the BNT162b2 (BioNTech/Pfizer) vaccine against SARS-CoV-2 infection 13 to 24 days after immunization in a real-world setting was assessed. Authors: Gabriel Chodick, Ph.D., of the…
Hospitalized individuals with active cancer more likely to die from COVID-19
Patients with blood cancers at greatest risk of COVID-19 death
A mechanism through which ‘good’ viruses kill ‘bad’ bacteria and block their reproduction
An important step in the battle against antibiotic-resistant bacteria
New study into green tea’s potential to help tackle COVID-19
As India continues to be ravaged by the pandemic, a Swansea University academic is investigating how green tea could give rise to a drug capable of tackling Covid-19.
Researcher gets $2.7 million grant to study seasonal and universal vaccination in aged populations
ATLANTA–Dr. Sang-Moo Kang, professor in the Institute for Biomedical Sciences at Georgia State University, has received a five-year, $2.7 million federal grant to study seasonal and universal vaccination in elderly populations with pre-existing immunity to influenza viruses. The grant from…
Social identity within the anti-vaccine movement
Researchers found a significant portion of Americans socially identify with the anti-vaxx label, presenting potential implications for public health
Extensive study identifies over a dozen existing drugs as potential COVID-19 therapies
FDA-approved drugs or experimental drugs with ample health data could be rapidly tested in humans for treatment of COVID-19
Pfizer-BioNTech vaccine recipients have lower antibody levels targeting the Delta variant
Levels of antibodies in the blood of vaccinated people that are able to recognise and fight the new SARS-CoV-2 Delta variant first discovered in India (B.1.617.2) are on average lower than those against previously circulating variants in the UK, according…
MASSACHUSETTS DERMATOLOGIST ESTABLISHES COVID-19 VACCINATION SITE FOR SCHOOL NURSES
Local board-certified dermatologist Louis Kuchnir, MD, FAAD, was honored as an American Academy of Dermatology Patient Care Hero for establishing a COVID-19 vaccination site in Marlborough, Mass. for school nurses at a time early in the vaccine rollout when vaccines were in short supply.
Luring bacteria into a trap
Developing vaccines against bacteria is in many cases much more difficult than vaccines against viruses. Like virtually all pathogens, bacteria are able to sidestep a vaccine’s effectiveness by modifying their genes. For many pathogens, such genetic adaptations under selective pressure…
Broadly neutralizing antibodies against pandemic flu point to new vaccine targets
A new study reveals that B cells can produce antibodies against the H1N1 influenza virus that also neutralize various other influenza strains, marking a development that could inform research into potential universal flu vaccines. The findings showed that the antibodies…
Centivax and US Naval Medical Research Center announce strategic partnership
Initiate clinical development of a broad-spectrum injectable for COVID-19, with $4.2M from the Henry Jackson Foundation
Clinical Trial Evaluating Mixed COVID-19 Vaccine Schedules Begins
NIH Trial to Evaluate Safety, Immunogenicity of Various Vaccine Booster Regimens
NIH launches clinical trial of universal influenza vaccine candidate
Nanoparticle vaccine developed by NIAID scientists
Safe laboratory-made molecules for global vaccination success
Chemists succeed in artificially manufacturing important building blocks for mRNA vaccines
Elucidating how the production of antibodies is regulated, one cell at a time
A study coordinated by Luís Graça, principal investigator at the Instituto de Medicina Molecular João Lobo Antunes (iMM; Portugal) and Professor at the Faculty of Medicine of the University of Lisbon (FMUL) used lymph nodes, tonsils and blood, to show…
Seropositivity following mRNA vaccination for SARS-CoV-2 in patients undergoing cancer treatment
What The Study Did: R ates of antispike antibody response to a messenger RNA SARS-CoV-2 vaccine in Israeli patients with cancer who are undergoing systemic treatment compared with healthy controls were evaluated in this study. Authors: Salomon M. Stemmer, M.D.,…
Technology that predicts protein stability is released by UK university spin-out company
A digital tool that will make it cheaper, safer and faster to develop new medicines is being rolled out by scientists from the University of Bath in the UK.
Cell mechanics research is making chemotherapy friendlier
Malignant tumour cells undergo mechanical deformation more easily than normal cells, allowing them to migrate throughout the body. The mechanical properties of prostate cancer cells treated with the most commonly used anti-cancer drugs have been investigated at the Institute of…
Pertussis more common in Europe than previously thought
Although vaccination programmes against pertussis are very effective in Europe, new Finnish study shows that the disease is still very common among middle-aged adults in various European countries. At the same time, the results show that the disease is underdiagnosed…
DNA vaccines for COVID-19 effective in mice, hamsters
Currently available COVID-19 vaccines rely on mRNA strands to teach the human immune system to recognize the SARS-CoV-2 virus. Now, researchers reporting in PLOS Neglected Tropical Diseases have reported the successful development of a vaccine that instead uses DNA encoding…
Versatile coronavirus antibody may be starting point for broader-acting vaccines
A special type of antibody is produced in patients who’ve had COVID-19 as well as less-serious coronaviruses that cause colds.
Study shows SARS-CoV-2 variants unlikely to affect T cell responses
In a new study, scientists at The Hong Kong University of Science and Technology (HKUST) have revealed that most T cell epitopes known to be targeted upon natural infection are seemingly unaffected by current SARS-CoV-2 variants.
Study affirms that vaccines are safe for children and adults
A new study looking across a large body of research finds further evidence for the safety of vaccines that are Food and Drug Administration-approved and routinely recommended for children, adults and pregnant women.
Real-world flight data shows continued need for social distancing
REYKJAVIK, Iceland 26 May 2021 – Current vaccination programmes alone will have a limited effect in stopping the second wave of COVID infections in the US, according to a study conducted by scientists from Reykjavik University, University of Lyon, University…
Research uncovers how ‘non-professional’ cells can trigger immune response
Worm cells sense changes in metabolism to activate defensive measures against pathogens
An inhalable nanobody-based treatment prevented and treated SARS-CoV-2 infections in hamsters
Inhalable Nanobody (PiN-21) prevents and treats SARS-CoV-2 infections in Syrian hamsters at ultra-low doses
Conquering COVID-19 with antivirals
The COVID-19 pandemic has seen scientists perform incredible feats in a short amount of time, from developing tests to new types of vaccines. Despite these victories, experts are still working to develop an effective antiviral drug to kill the SARS-CoV-2…
Health officials release guide to build COVID-19 vaccine trust among nursing home workers
WASHINGTON – May 26, 2021 – A new research-based guide is available to increase uptake of the COVID-19 vaccine among nursing home workers. Invest in Trust: A Guide for Building COVID-19 Vaccine Trust and Increasing Vaccination Rates Among CNAs addresses…
A comprehensive profile of California’s ‘homegrown’ coronavirus
New analysis suggests the California variant is more transmissible than unmutated strains, but vaccines are effective against it
HKUST’s meta-analysis shows SARS-CoV-2 variants unlikely to affect T cell responses
In a new study, scientists at The Hong Kong University of Science and Technology (HKUST) have revealed that most T cell epitopes known to be targeted upon natural infection are seemingly unaffected by current SARS-CoV-2 variants. In their latest research,…
Accessibility, usability of state health department COVID-19 vaccine websites
What The Study Did: Researchers analyzed each state’s department of health website for accessibility and usability challenges. Findings suggest s tate health department COVID-19 vaccine website accessibility and usability challenges create frustration, may promote health disparities and contribute to overall…
Ultra-low doses of inhaled nanobodies effective against COVID-19 in hamsters
PITTSBURGH, May 26, 2021 – In a paper published today in Science Advances , researchers from the University of Pittsburgh School of Medicine showed that inhalable nanobodies targeting the spike protein of the SARS-CoV-2 coronavirus can prevent and treat severe…
Older Canadians say they’re more willing to get the flu shot in the wake of COVID-19
The pandemic has increased older adults’ willingness to receive the flu shot, new research shows. The study analyzed survey results of 4,501 Canadians over the age of 50 from ten provinces. Twenty per cent of 1,001 research participants aged 50…