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UrduThe laboratory of Hai-Hui “Howard” Xue at the CDI published the findings of the complex and cascading molecular interactions modulating T-cell immunology in the August issue of the journal Nature Immunology.
Tag: Vaccine
Newly Discovered “Danger Signal” May Spur Vaccine Development and Allergy Treatment
A team of Rutgers researchers and others inject parasitic worms into mice to study how injured cells trigger an immune response.
In brief: COVID-19 vaccine does not negatively affect placental health
Vaccination against COVID-19 had no impact on the health of placentas in pregnant women, according to new research by pathologists at Weill Cornell Medicine and NewYork-Presbyterian.
Pfizer-BioNTech and AstraZeneca vaccines offer high protection against severe COVID-19, 6 months after second doses, finds study of over 7 million adults
Protection against severe COVID-19 by two doses of Pfizer-BioNTech and AstraZeneca COVID-19 vaccines remained high up to six months after second doses, finds new research which analysed NHS health record data on over seven million adults. Reassuringly, the University of Bristol-led study published in The BMJ today [July 20], found protection in older adults aged over 65 years, and in clinically vulnerable adults.
Adults with blood cancers respond to booster, not initial dose of COVID-19 vaccine
Most patients in the study mounted immune responses after a booster dose, and no patient with antibody responses died from COVID-19.
Study explores unusual interaction between viruses, live vaccines
A study of a herpes virus that infects chickens offers new insights into potentially problematic interactions between vaccines made from live viruses and the viruses they are meant to thwart.
Age may rival politics in COVID-19 vaccine debate
New research from the University of Georgia suggests age and risk perception may have as much of an effect on COVID-19 vaccine acceptance as party affiliation.
South Asian Communities in GTA disproportionately hit by COVID-19
A COVID CommUNITY – South Asian study, published in the Canadian Medical Association Journal (CMAJ) Open has found that South Asian communities living in the Greater Toronto Area (GTA) suffered disproportionately from COVID-19 in the first year of the pandemic.
COVID-19 vaccine protects people of all body weights from hospitalization and death, study of 9 million adults in England suggests
COVID-19 vaccines greatly reduced the number of cases of severe COVID-19 disease for everyone regardless of their body size, according to a new study published in The Lancet Diabetes & Endocrinology. Vaccine effectiveness was similar for those with a higher BMI and of a healthy weight, but slightly lower in the underweight group, who were also the least likely to have been vaccinated.
New universal flu vaccine offers broad protection against influenza A virus infections, researchers find
A new universal flu vaccine constructed with key parts of the influenza virus offers broad cross protection against different strains and subtypes of influenza A viruses in young and aged populations, according to a new study by researchers in the Institute for Biomedical Sciences at Georgia State University.
Interrupting the Treatment of Vulnerable People on Immune-Suppressing Medicines, Doubles Their Antibody Response to COVID-19 Booster Vaccination
A major clinical trial, led by experts at the University of Nottingham working in partnership with several Universities and NHS hospitals, has found that by interrupting the treatment of vulnerable people on long-term immune supressing medicines for two weeks after a COVID-19 booster vaccination, their antibody response to the jab is doubled.
Immune Molecules From a Llama Could Provide Protection Against a Vast Array of SARS-like Viruses Including COVID-19, Researchers Say
Mount Sinai-led researchers have shown that tiny, robust immune particles derived from the blood of a llama could provide strong protection against every COVID-19 variant, including Omicron, and 18 similar viruses.
University of Pennsylvania’s First NFT Commemorates mRNA Research
The historic scientific breakthrough at the Perelman School of Medicine at the University of Pennsylvania that helped lead the world’s fight against COVID-19 through mRNA-based vaccines is being commemorated through a non-fungible token—a digital asset to be auctioned by Christie’s—that will support ongoing research at Penn.
Loyola Medicine Pediatric Experts Available to Discuss Possible Approval of COVID-19 Vaccines for Children Under 5
MAYWOOD, IL – Panels from the Food and Drug Administration (FDA) and the Centers for Disease Control (CDC) are meeting this week to consider authorizing COVID-19 vaccines for children under the age of 5 from both Pfizer and Moderna. The…
Mount Sinai Researchers Develop a Rapid Test to Measure Immunity to COVID-19
Mount Sinai researchers have developed a rapid blood assay that measures the magnitude and duration of someone’s immunity to SARS-CoV-2, the virus that causes COVID-19. This test will allow large-scale monitoring of the population’s immunity and the effectiveness of current vaccines to help design revaccination strategies for vulnerable immunosuppressed individuals, according to a study published in Nature Biotechnology in June.
Heart Failure Patients Unvaccinated Against COVID-19 Are Three Times More Likely to Die From It Than Boosted Heart Failure Patients
EMBARGOED UNTIL JUNE 9, 2022, 10AM EST (New York, NY – June 9, 2022) – Heart failure patients who are unvaccinated against SARS-CoV-2, the virus that causes COVID-19, are three times more likely to die if infected with the virus…
Data contradict fears of COVID-19 vaccine effects on pregnancy and fertility
Study adds further evidence that vaccination is protective and safer than COVID-19 infection.
Study shines light on longevity of COVID-19 immune response
By uniting research from 8 cohorts across the U.S., a group of researchers has accelerated collection of data integral in answering questions about immune responses needed for long lasting protection from SARS-CoV-2.
Cleveland Clinic Appoints Ted Ross, Ph.D., as Global Director of Vaccine Development
Ted Ross, Ph.D., has been appointed Global Director of Vaccine Development at Cleveland Clinic.
In this newly created role, he will lead the development of novel vaccine platforms for a variety of infectious diseases, including influenza, HIV and COVID-19. A highly renowned scientist with expertise in virology, vaccines, immunology and microbiology, Dr. Ross’ research focuses on the design of new vaccines and the implementation of new vaccine trials.
True and false claims: online behaviors behind COVID-19 vaccine uptake
Vaccine uptake constitutes a key barometer as governments lead the communities out of the COVID-19 pandemic. Facts and fake news have apparently influenced vaccination willingness. But how valid is this proposition?
Flu Season Underway Amid Ongoing COVID-19 Pandemic
For the second straight year, flu season is emerging against the backdrop of the COVID-19 pandemic. While the number of flu cases was relatively low last year, experts at Johns Hopkins Medicine say that this year, it could be much higher.
New COVID vaccine design is easier to manufacture, doesn’t need cold storage
Currently available COVID vaccines require cold storage and sophisticated manufacturing capacity, which makes it difficult to produce and distribute them widely, especially in less developed countries.
In Covid-19 Vaccinated People, Those with Prior Infection Likely to Have More Antibodies
In what is believed to be one of the largest studies of its kind, Johns Hopkins Medicine researchers have shown that antibody levels against SARS-CoV-2 (the COVID-19 virus) stay more durable — that is, remain higher over an extended period of time — in people who were infected by the virus and then received protection from two doses of messenger RNA (mRNA) vaccine compared with those who only got immunized.
For people of color in L.A., misinformation, past injustices contribute to vaccine hesitancy
New UCLA research finds that misinformation and politicization, awareness of past injustices involving medical research, and fears about the inequitable distribution of vaccines all contributed to hesitancy to be vaccinated among Los Angeles’ People of Color.
Vaccinating children against COVID-19 can prevent tragedy
Three in 10 parents say they will “definitely not” get their 5- to 11-year-old vaccinated against COVID-19, according to new data from the Kaiser Family Foundation. Neil Lewis, Jr., a behavioral scientist at Cornell University who was not involved with…
Expert available to comment on Pfizer’s COVID-19 vaccine for kids
Dr. Ishminder Kaur Dr. Kaur is an assistant professor of pediatrics in the division of infectious diseases at the David Geffen School of Medicine at UCLA and the medical director of the pediatric antimicrobial stewardship program at UCLA Mattel Children’s…
COVID-19: Does having received the BCG vaccine as a child provide a protective effect?
Being vaccinated during childhood with the BCG (Bacille Calmette-Guérin) vaccine against tuberculosis is not a long-term protective factor against COVID-19, despite what was thought at the beginning of the pandemic.
Cleveland Clinic Launches First-of-its Kind Preventive Breast Cancer Vaccine Study
Cleveland Clinic researchers have opened a novel study for a vaccine aimed at eventually preventing triple-negative breast cancer, the most aggressive and lethal form of the disease.
COVID vaccine booster increases antibody responses, is protective in rhesus macaques
A booster dose of the mRNA-1273 COVID-19 vaccine given to rhesus macaques about six months after their primary vaccine series significantly increased levels of neutralizing antibodies against all known SARS-CoV-2 variants of concern, according to a new study from National Institutes of Health scientists and colleagues.
Hepatitis A Vaccination Required for Herd Immunity in People Experiencing Homelessness or Who Use Drugs
In the U.S., hepatitis A outbreaks are repeatedly affecting people experiencing homelessness or who use drugs. A 2017-19 Kentucky outbreak primarily among these groups resulted in 501 cases, six deaths. Vaccination efforts likely averted 30 hospitalizations and $490K in costs,…
Rutgers Chancellor Available to Discuss COVID-19 Booster Shots, Why Frontline Workers Need Them
Brian L. Strom, chancellor at the Rutgers Biomedical and Health Sciences and executive vice president for Rutgers Health Affairs, is available to discuss the COVID-19 booster shot and why frontline workers need to get them. Strom agrees with the Centers…
Long COVID symptoms in children rarely persist beyond 12 weeks
Long COVID symptoms rarely persisted beyond 12 weeks in children and adolescents unlike adults. But more studies were required to investigate the risk and impact of long COVID in young people to help guide vaccine policy decisions in Australia, according to a review led by the Murdoch Children’s Research Institute (MCRI).
Vaccines for kids: Pfizer announcement good for schools, parents
Pfizer announced vaccinated children, aged 5 to 11, showed evidence of protection against the coronavirus. The data must be reviewed by the FDA before kids can be inoculated, but signals promise says Dr. Isaac Weisfuse, medical epidemiologist at Cornell University.…
Link between menstrual changes after COVID-19 vaccination is plausible and should be investigated
Some women say their periods change after getting a covid-19 vaccination.
COVID-19 nasal vaccine candidate effective at preventing disease transmission
Breathe in, breathe out. That’s how easy it is for SARS-CoV-2, the virus that causes COVID-19, to enter your nose.
Fact Check on claim about COVID-19 vaccines
While it is true that the vaccines are effective at prevention of serious illness, many studies show that they are also effective at preventing asymptomatic infection. That is, vaccines are effective at preventing you from catching COVID-19, and therefore reduce the risk that you transmit to others.
The Lancet: Scientific evidence to date on COVID-19 vaccine efficacy does not support boosters for general population, expert review concludes
An expert review by an international group of scientists, including some at the WHO and FDA, concludes that, even for the delta variant, vaccine efficacy against severe COVID is so high that booster doses for the general population are not appropriate at this stage in the pandemic.
As more US adults intend to have covid vaccine, national study also finds more people feel it’s not needed
A peer-reviewed analysis of US national survey data of 75,000 adults shows, from early January to late March, a near “18 percentage point” increase of adults who have either had the COVID-19 vaccine jab or are willing to do have it.
“Automated Vaccine Filling Machine”, An Innovation from Chulalongkorn University, Helps Boost the Number of Vaccinations by 20 Percent, and Reduce the Workload of Medical Personnel
The Faculty of Engineering, Chulalongkorn University has developed an automated vaccine filling machine that can fill AstraZeneca vaccine into syringes with precision, speed, and safety, helping to increase the number of vaccinated people by 20 percent. The prototype is now operating at Chula Vaccination Center and more machines are planned to be built to support frontline medical personnel in many vaccination centers soon.
Rapid and sensitive on-site measurement of antibodies against the COVID-19 virus
A research team at the RIKEN Center for Emergent Matter Science (CEMS) in Japan has developed a diagnostic system that can rapidly and sensitively measure the amount of antibodies in the blood that can protect us from SARS-CoV-2, the virus that causes COVID-19.
Double vaccination halves risk of Long COVID
Adults who have received a double vaccination are 49% less likely to have Long COVID should they contract a COVID-19 infection.
New study: Nursing home residents, health care workers lose more than 80% of their COVID-19 immunity six months after Pfizer vaccine
A new, multi-institutional study led by Case Western Reserve University—in partnership with Brown University—found that COVID-19 antibodies produced by the Pfizer vaccine decreased sharply in senior nursing home residents and their caregivers six months after receiving their second shots.
The Wistar Institute Recruits Vaccine Researcher Amelia Escolano, Ph.D., and Immunologist Nan Zhang, Ph.D., as Assistant Professors
Wistar welcomes Amelia Escolano, Ph.D., and Nan Zhang, Ph.D., as assistant professors.
COVID-19 Vaccine Effectiveness Dips, But Remains Potent Disease Deterrent
COVID-19 vaccines remain effective, but their potency has diminished in recent months, according to a nationwide study at eight sites, including Salt Lake City, Utah.
Fertility and COVID-19 Vaccination: Experts Weigh In
Fertility and pregnancy were often stressful topics even before the COVID-19 pandemic began, but now, many who are pregnant or hoping to become pregnant have questions about how to protect themselves from the virus while keeping their reproductive goals in mind.
Breast milk of mothers who received COVID-19 vaccine contains antibodies that fight illness
The breast milk of lactating mothers vaccinated against COVID-19 contains a significant supply of antibodies that may help protect nursing infants from the illness, according to new research from the University of Florida.
Faculty Receive Grant to Assess COVID-19 Vaccine Uptake in Sexual and Gender Minorities
Rutgers School of Public Health dean, Perry N. Halkitis, and Center for Health, Identity, Behavior and Prevention Studies deputy director, Kristen D. Krause, have received a grant from the Merck & Co., Inc., Kenilworth, NJ, USA (known as MSD outside the United States and Canada) Investigator Studies Program (MISP) to examine COVID-19 and HPV vaccine uptake in sexual and gender minority populations living in New Jersey.
Surveillance study finds disparities, high proportion of past COVID-19 infections among adults and children in Santa Ana
In a large-scale, population-based surveillance conducted in partnership with the City of Santa Ana, researchers at the University of California, Irvine’s Program in Public Health found 27% positivity of SARS-CoV-2 antibodies among participating Santa Ana residents. This unique study was one of the first to examine household transmission of COVID-19 and to include a pediatric population (ages 5+).
COVID-19 mRNA Vaccine that Uses Fundamental Penn Technology Receives FDA Approval
PHILADELPHIA – The U.S. Food and Drug Administration (FDA) has given the first full approval to a COVID-19 mRNA vaccine, which uses modified mRNA technology invented and developed by scientists in the Perelman School of Medicine at the University of Pennsylvania, whose years of research in mRNA science laid a critical piece of the foundation for the largest global vaccination campaign in history.
Statement from Jesse L. Goodman, MD, MPH, on FDA Approval of Pfizer-BioNTech’s COVID-19 Vaccine
Today, the US Food & Drug Administration approved the two-dose COVID-19 Pfizer-BioNTech vaccine. Jesse L. Goodman, MD, MPH, professor of medicine and infectious diseases at Georgetown University Medical Center and former FDA Chief Scientist comments. (Audio file available)