InDepth Pharmaceuticals, founded by Deepak Nihalani, Ph.D., the SmartState Endowed Chair in Renal Disease Biomarkers at the Medical University of South Carolina (MUSC), has taken a vital step toward commercializing an innovative diagnostic technique that could better predict kidney transplant…
Tag: Transplantation
InDepth Pharmaceuticals moves ahead with diagnostic to predict kidney transplant success
InDepth Pharmaceuticals, founded by Deepak Nihalani, Ph.D., the SmartState Endowed Chair in Renal Disease Biomarkers at the Medical University of South Carolina (MUSC), has taken a vital step toward commercializing an innovative diagnostic technique that could better predict kidney transplant…
Artificial muscle sheets transform stem cells into bone
Programmable biomaterials for bone regeneration introduced
Artificial muscle sheets transform stem cells into bone
Programmable biomaterials for bone regeneration introduced
Artificial muscle sheets transform stem cells into bone
Programmable biomaterials for bone regeneration introduced
Massachusetts General Hospital performs first-of-its-kind heart transplant in New England
BOSTON — A team of surgeons and specialists at Massachusetts General Hospital (MGH) is announcing an achievement in transplant surgery today, having recently performed the largest number of adult heart transplants in the country using what are known as Donation…
Discovery of gene that modifies the severity of inherited kidney disease
Scientists have developed a new way to understand complex genetic diseases and have identified a gene that modifies the severity of inherited kidney disease, paving the way for personalised treatments. Experts at Newcastle University, UK, have shown that the rate…
Discovery of gene that modifies the severity of inherited kidney disease
Scientists have developed a new way to understand complex genetic diseases and have identified a gene that modifies the severity of inherited kidney disease, paving the way for personalised treatments. Experts at Newcastle University, UK, have shown that the rate…
‘Gift of life’ marketing fails to motivate many donors
Blood and organ donors are thin on the ground but maybe better marketing could help: QUT researchers
Online patient tool is associated with increased likelihood of receiving kidney transplant
Hemodialysis patients who use an online patient portal are more likely to receive a donor kidney transplant and reduce wait times for an operation than non-users of the tool, according to Journal of the American College of Surgeons research findings
Online patient tool is associated with increased likelihood of receiving kidney transplant
Hemodialysis patients who use an online patient portal are more likely to receive a donor kidney transplant and reduce wait times for an operation than non-users of the tool, according to Journal of the American College of Surgeons research findings
New research may lead to increased use of available hearts for transplant
Number of children who die waiting for hearts could drop dramatically
New research may lead to increased use of available hearts for transplant
Number of children who die waiting for hearts could drop dramatically
MEDITERRANEAN DIET MAY HELP PRESERVE THE KIDNEY HEALTH OF TRANSPLANT RECIPIENTS
• In a study of kidney transplant recipients, those with higher adherence to the Mediterranean diet were less likely to experience kidney function loss.
Hepatitis C-positive donors a viable option to expand heart donor pool
Patients who were transplanted with hearts from hepatitis C-positive donors had comparable outcomes after one year to patients who received hearts from donors that didn’t have the disease, according to a Vanderbilt University Medical Center study published in JAMA Cardiology…
Hepatitis C-positive donors a viable option to expand heart donor pool
Patients who were transplanted with hearts from hepatitis C-positive donors had comparable outcomes after one year to patients who received hearts from donors that didn’t have the disease, according to a Vanderbilt University Medical Center study published in JAMA Cardiology…
Heart transplants from donors positive for hepatitis C
What The Study Did: Researchers at Vanderbilt University Medical Center in Nashville, Tennessee, report in this case series on 80 patients who had heart transplants using hearts from donors positive for hepatitis C. To access the embargoed study: Visit our…
Heart transplants from donors positive for hepatitis C
What The Study Did: Researchers at Vanderbilt University Medical Center in Nashville, Tennessee, report in this case series on 80 patients who had heart transplants using hearts from donors positive for hepatitis C. To access the embargoed study: Visit our…
A test of a customized implant for hip replacement
Scientists developed a mathematical model of an ‘endoprosthesis-skeleton’ system; special attention was paid to the geometry and internal structure of hip bones
A test of a customized implant for hip replacement
Scientists developed a mathematical model of an ‘endoprosthesis-skeleton’ system; special attention was paid to the geometry and internal structure of hip bones
Air pollution may increase mortality risk after heart transplant
Heart transplant recipients in high air pollution areas are more likely to die from infections
Treatment with PD-1 prior to stem cell transplant is safe for Hodgkin lymphoma patients
Post-transplant treatment with cyclophosphamide reduces rates of acute GVHD and relapse
Air pollution may increase mortality risk after heart transplant
Heart transplant recipients in high air pollution areas are more likely to die from infections
Treatment with PD-1 prior to stem cell transplant is safe for Hodgkin lymphoma patients
Post-transplant treatment with cyclophosphamide reduces rates of acute GVHD and relapse
The next step in organ transplants: New startup takes aim at reperfusion injury
Charleston, SC-based Lydex Pharmaceuticals has received a small business technology transfer grant from the NIH to investigate and develop compounds targeting key enzymes responsible for organ damage, inflammation and rejection after transplant
Using lungs from increased-risk donors expands donor pool, maintains current survival rates
Currently, there are nearly 1,500 people waiting for a lung transplant in the US
Using lungs from increased-risk donors expands donor pool, maintains current survival rates
Currently, there are nearly 1,500 people waiting for a lung transplant in the US
A big step toward curbing graft-vs.-host disease after bone marrow transplant
Abatacept, currently used for arthritis, gains FDA Breakthrough Therapy Designation for acute GVHD prevention
A big step toward curbing graft-vs.-host disease after bone marrow transplant
Abatacept, currently used for arthritis, gains FDA Breakthrough Therapy Designation for acute GVHD prevention
Researchers create ‘smart’ surfaces to help blood-vessel grafts knit better, more safely
HAMILTON, ON, Nov. 27, 2019 – Researchers at McMaster University have created a new coating to prevent clotting and infection in synthetic vascular grafts, while also accelerating the body’s own process for integrating the grafted vessels. Variants of the coating…
Fred Hutch at ASH: Latest CAR T data – BCMA, CD19, CD20 – plus new insights on transplantation, gene therapy – and more
The 61st American Society of Hematology Annual Meeting and Exposition will take place Dec. 7–10 in Orlando, Florida
Tailored T-cell therapies neutralize viruses that threaten kids with PID
Tailored T-cells specially designed to combat a half dozen viruses are safe and may be effective in preventing and treating multiple viral infections, according to research led by Children’s National Hospital faculty. Catherine Bollard, M.B.Ch.B., M.D., director of the Center…
Tailored T-cell therapies neutralize viruses that threaten kids with PID
Tailored T-cells specially designed to combat a half dozen viruses are safe and may be effective in preventing and treating multiple viral infections, according to research led by Children’s National Hospital faculty. Catherine Bollard, M.B.Ch.B., M.D., director of the Center…
New study casts doubt on China’s organ donation data
The Chinese government may have been systematically misreporting the number of organs it claims it has voluntarily collected since 2010, according to new research published in BMC Medical Ethics . In 2015 China promised the world they would no longer…
New study casts doubt on China’s organ donation data
The Chinese government may have been systematically misreporting the number of organs it claims it has voluntarily collected since 2010, according to new research published in BMC Medical Ethics . In 2015 China promised the world they would no longer…
Inhaled immunosuppressant may increase survival, pulmonary function after lung transplant
University of Maryland School of Medicine researchers test exploratory drug-device combination to prevent lung-destroying airway inflammation
Inhaled immunosuppressant may increase survival, pulmonary function after lung transplant
University of Maryland School of Medicine researchers test exploratory drug-device combination to prevent lung-destroying airway inflammation
Hospitals given latitude to select transplant candidates don’t prioritize sickest patients
Analysis of the US heart transplant system shows how hospitals can take advantage of organ allocation rules so that less critically ill patients receive higher priority for transplants
Hospitals given latitude to select transplant candidates don’t prioritize sickest patients
Analysis of the US heart transplant system shows how hospitals can take advantage of organ allocation rules so that less critically ill patients receive higher priority for transplants
Better Biosensor Technology Created for Stem Cells
Rutgers innovation may help guide treatment of Alzheimer’s, Parkinson’s diseases
Better Biosensor Technology Created for Stem Cells
Rutgers innovation may help guide treatment of Alzheimer’s, Parkinson’s diseases
University of Cincinnati finds new option for liver transplant patients
Common drug offers fewer side effects than prednisone, but similar organ rejection rates in liver transplants in preliminary studies
Stem cell transplants used to grow fully functional lungs in mice
Researchers at Columbia University were able to grow fully functional lungs in mouse embryos using transplanted stem cells. The findings suggest that it may be ultimately possible to use the technique to grow human lungs in animals for patients who…
Implantable artificial kidney achieves preclinical milestone
The Kidney Project, a national effort to develop an implantable bio-artificial kidney that could eliminate the need for dialysis, will announce a key milestone in a November 7, 2019 presentation at the American Society of Nephrology Kidney Week 2019 conference…
As large chains grow to dominate dialysis, patient outcomes decline
Acquisitions by for-profit dialysis companies hurt patient health, survival and transplant rates
Study Examines Variation in Transplant Centers’ Use of Less-Than-Ideal Organs
• In 2010-2016, many U.S. transplant centers commonly accepted deceased donor kidneys with less desirable characteristics.
• The use of these organs varied widely across transplant centers, however, and differences were not fully explained by the size of waitlists or the availability of donor organs.
First application of genetically modified, live-cell, pig skin to a human wound
BOSTON – Burn specialists at Massachusetts General Hospital (MGH) announced today they have successfully used live-cell, genetically engineered pig skin (xenograft) for the temporary closure of a burn wound. Through an FDA-cleared phase one clinical trial led by surgeon Jeremy…
Long-term outcomes for transplant patients who receive high-risk donor lungs
What The Study Did : Researchers compared long-term outcomes between transplant patients who received conventional donor lungs and those who received high-risk donor lungs that had been assessed and reconditioned outside the body through a technique known as ex vivo…
Fourth baby born after uterus transplant at Baylor University Medical Center in Dallas
Family of fourth baby shares their story of hope
World’s first three-organoid system opens doors for medical research and diagnosis
Scientists at Cincinnati Children’s use stem cells to grow connected, functioning set of miniature human liver, pancreas, biliary ducts