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UrduNUI Galway study, published in the international journal Scientific Reports, confirms that spiders carry harmful bacteria and that they can be transmitted when a spider uses its fangs to bite
Tag: TOXICOLOGY
Bleach-alternative COVID-19 surface disinfectants may pollute indoor air: USask research
Cleaning surfaces with hydrogen peroxide-based disinfectants has the potential to pollute the air and pose a health risk, according to research led by University of Saskatchewan (USask). The research team found that mopping a floor with a commercially available hydrogen…
Environmental exposures affect therapeutic drugs
High-resolution mass spectrometry promotes new methods for analysis
Antimicrobial Soap Additive Worsens Fatty Liver Disease in Mice
Triclosan, an antimicrobial found in many soaps and other household items, worsens fatty liver disease in mice fed a high-fat diet.
Tarantula toxin attacks with molecular stinger
Venom immobilizes prey by interfering with sodium channels that generate electrical signals in the animal’s nerve cells
E-cigarette Users at Greater Risk of Poor Immune Response to Viruses
In a controlled study, scientists found that smokers and e-cigarette users exhibited significantly altered immune responses to a model of influenza virus infection, suggesting increased susceptibility to disease, including COVID-19
Microbial remedies target chemical threats in the environment
Across America, hazardous waste sites pose an ongoing threat to human and environmental health. The most severe cases are known as Superfund sites, of which over a thousand currently exist. Some 50 million Americans live within three miles of one…
Childhood lead exposure leads to structural changes in middle-aged brains
Study participants had higher lead exposures typical for the 1970s
Are e-cigarette users at greater risk of poor immune response to flu, COVID?
Led by Meghan Rebuli, Ph.D., and Ilona Jaspers, Ph.D., UNC School of Medicine, researchers found that vaping electronic cigarettes could impair the body’s normal immune response to viral infections
Evidence shows human transmission in deadly outbreak of mysterious disease in Bolivia
At TropMed2020, scientists describe rush to gauge risks of Chapare virus, an emerging hemorrhagic fever seen previously in only one patient
In Mice, Cadmium Exposure During Pregnancy Linked to Obesity, Metabolic Issues in Adult Female Offspring
In a mouse study aimed at modeling human exposure to the toxic metal cadmium, researchers found that female offspring of mice exposed to cadmium during pregnancy became obese in adulthood, developed fatty livers and could not process glucose normally. Male offspring were not affected in the same way.
3D printing — a ‘dusty’ business?
Communication No 050/2020 from the BfR of Nov. 6, 2020
In mice, cadmium exposure during pregnancy linked to obesity in female offspring
In a mouse study aimed at modeling human exposure to the toxic metal cadmium, researchers from North Carolina State University found that female offspring of mice exposed to cadmium during pregnancy became obese in adulthood, developed fatty livers and could…
Researchers light-up mouse brain, revealing previously hidden areas susceptible to opioids
Study is the first to apply CLARITY technique followed by three-dimensional (3D) fluorescent imaging to better understand opioid receptor localization across the whole brain in 3D images
Metal pollution in British waters may be threatening scallops, study reveals
Metal pollution from historic mining appears to be weakening scallop shells and threatening marine ecosystems in an area off the coast of the Isle of Man, a major new study suggests.
Water fleas on ‘happy pills’ have more offspring
All those medicines we take? A lot end up in treated wastewater — with sometimes surprising results
Paracetamol poisonings up
Paracetamol is a popular source of pain relief. In Switzerland, it is available over the counter in 500 milligram tablets, but also in double the dose, in 1,000 milligram (1 gram) tablets when prescribed by a physician. Researchers at ETH…
Surprising players in acute liver failure point to potential treatment
Gut microbes and host cells jointly contribute to the progression of this mostly incurable disease
Dartmouth study examines well water testing promotion in pediatric primary care
Findings from a new study conducted by a team of researchers at Dartmouth’s Geisel School of Medicine and published in the journal Preventive Medicine Reports , show that involving pediatric practices in the promotion of private well water testing can…
Bioplastics no safer than other plastics
Bioplastics may be produced from oil, but that’s about the only benefit, researchers say
Project to investigate Southeast Asia plastic pollution
Researchers have launched an ambitious project to discover the impacts of plastic pollution in the oceans of Southeast Asia – and how the problem might be tackled. An international team led by the University of Exeter and the National University…
UMass Lowell secures $11.7 million in research funding
Federal support goes to projects to protect military personnel
New PETA Grant Honors EPA Administrator
Wheeler Scholarship Will Help Scientists Develop Non-Animal Test Methods
Vitamin D: Consumption of high-dose food supplements is unnecessary
BfR Opinion No 035/2020 issued July 31, 2020
Study: More than 200 million Americans could have toxic PFAS in their drinking water
WASHINGTON – A peer-reviewed study by scientists at the Environmental Working Group estimates that more than 200 million Americans could have the toxic fluorinated chemicals known as PFAS in their drinking water at a concentration of 1 part per trillion,…
Agricultural Toxicity, Hepatic Effects of Phenobarbital, and More Featured in October 2020 Toxicological Sciences
Toxicological Sciences features leading research biotransformation, toxicokinetics, and pharmacokinetics; computational toxicology and databases; mixtures toxicology; and more in the October 2020 issue.
Study Shows Proof of Concept of BioIVT HEPATOPAC Cultures with Targeted Assay to Evaluate
New in vitro Bioactivation Liver Response Assay used HEPATOPAC model to demonstrate utility of in vitro transcriptomic signature-based strategy in preclinical DILI risk assessment
Researchers find consistent mercury levels in arctic seals
Ringed seals and other Arctic marine mammals are important in the diet of Arctic Indigenous peoples. A study spanning 45 years of testing indicates that mercury concentrations in ringed seals from the Canadian Arctic have remained stable, showing very limited…
Smoke Chemistry, In Vitro Cytotoxicity, and Genotoxicity Demonstrate Enhanced Toxicity of Cigarillos Compared to Cigarettes
This study found that there is significantly greater toxicity in the tested US-marketed cigarillos than cigarettes for tobacco constituent levels, cytotoxicity, and genotoxicity. These findings are important, not only for improved understanding of the toxicity from the use of cigarillos…
Tattoo inks: risk assessment for Pigment Blue 15:3 and Pigment Green 7
BfR Opinion No 039/2020 issued 8 September 2020
Evidence of Alzheimer’s, Parkinson’s & MND in brains of young people exposed to dirty air
Researchers looking at the brainstems of children and young adults exposed lifelong to air pollution in Mexico City have discovered disturbing evidence of harm.
Laundry lint can cause significant tissue damage within marine mussels
Microscopic fibres created during the laundry cycle can cause damage to the gills, liver and DNA of marine species, according to new research. Scientists at the University of Plymouth exposed the Mediterranean mussel ( Mytilus galloprovincialis ), found in various…
800 million children still exposed to lead
UNICEF study documents a persistent, dangerous problem
Our health: New focus on the synergy effect of nanoparticles
Nanoparticles are valuable and useful in many products, but according to a new study, they can also damage our cells. Researchers are concerned about the effect of lifelong exposure to the human organism.
Project aims to reveal the fate of tire particles in the marine environment
Tyre particles are believed to transfer in large quantities from vehicles into our rivers and oceans. However, their precise fate – and the impact they have – remains something of a mystery. Now a three-year project funded by the Natural…
Videos most effective in communicating with parents about secondhand smoke risks
The best way to communicate with parent smokers about the risks of secondhand smoke to their children is to use videos depicting the risks, as well as solutions to reduce those risks. Those were the findings of a study, published…
Computer model shows how COVID-19 could lead to runaway inflammation
PITTSBURGH, Sept. 29, 2020 – A study from the University of Pittsburgh School of Medicine and Cedars-Sinai addresses a mystery first raised in March: Why do some people with COVID-19 develop severe inflammation? The research shows how the molecular structure…
Tests indicate modern oral nicotine products elicit lower toxicity responses than cigs
New research by BAT indicates that modern oral products (MOPs) showed lower toxicity responses in certain assays than traditional cigarettes. Scientists analysed the toxicological impact of one of BAT’s nicotine pouch products, formerly called Lyft and now known as Velo,…
Potential drug target for dangerous E. coli infections identified
Escherichia coli, known as E. coli, are bacteria which many people associate with causing mild food poisoning, but some types of E. coli can be fatal.
First evidence that air pollution particles and metals are reaching the placenta
Pollution particles, including metals, have been found in the placentas of fifteen women in London, according to research led by Queen Mary University of London.
First evidence that air pollution particles and metals are reaching the placenta
Pollution particles, including metals, have been found in the placentas of fifteen women in London, according to research led by Queen Mary University of London
T Cell Therapy, Gut Microbiome, Tumorigenicity, and More Featured in September 2020 Toxicological Sciences
Toxicological Sciences features leading research in toxicology in the areas of biomarkers, environmental toxicology, and more in the September 2020 issue.
Integral molecular awarded grant from the Commonwealth of PA to advance COVID-19 research
PHILADELPHIA – Integral Molecular has been awarded $521,723 from the Commonwealth of Pennsylvania to leverage its technologies in the global fight against COVID-19. Integral Molecular is at the forefront of the fight against COVID-19, with their technologies being used by…
Potent drug supply drop, not domestic drug policies, likely behind 2018 OD death downturn
PITTSBURGH, Sept. 16, 2020 – The slight decline in drug overdose deaths in 2018 coincided with changing Chinese regulations on a powerful type of opioid, rather than the result of U.S. efforts to curb the overdose epidemic, a University of…
There’s no place like home: Cleaning toxic tobacco smoke residue in our homes
San Diego, CA – The COVID-19 pandemic has created a number of challenges, including that many are spending more time at home than ever before. This is a significant problem for those with neighbors who smoke. Smoking continues to be…
uOttawa Ph.D. student receives Fire Researcher of the Year Award
Jennifer Keir, a uOttawa PhD student and Research Associate whose research investigates firefighters’ health and their occupational exposure to hazardous substances, has been named the 2020 Fire Researcher of the Year by the Canadian Fire Chiefs Association. In October 2017,…
Consumption of sheep or beef liver can contribute considerably to the total intake of PFAS
BfR Opinion no. 028/2020 issued 6 July 2020
Detection of PCBs and their metabolites (OH-PCBs) in the fetal brain of a Japanese macaque
Mother to fetus transfer of OH-PCBs in the Japanese macaque: Extrapolation of Exposure Scenarios for Humans
Toxic metals can affect student health performance, say scientists from RUDN university
A group of medical and environmental researchers from RUDN University evaluated the level of heavy metals in the organism of first-year university students from different countries of the world. The results of the screening helped the scientists to reveal a…
Skin creams, make-up and shampoos should be free from Pluralibacter
Updated BfR Opinion No 038/2020 issued 7 September 2020