AACR 2023: Ohio State experts share new findings on immuno-oncology, ‘smart-drugs,’ obesity-related endometrial cancers and other research topics

New smart-drug treatment options for pancreatic cancer, immuno-oncology treatments and real-time immune-monitoring strategies are among the research topics to be presented by investigators at The Ohio State University Comprehensive Cancer Center – Arthur G. James Cancer Hospital and Richard J. Solove Research Institute (OSUCCC – James) at the American Association for Cancer Research (AACR) annual meeting held April 14-19 at the Orange County Convention Center in Orlando, Florida.

Identifying Potential Treatment for Triple Negative Breast Cancer

Researchers at Rutgers Cancer Institute of New Jersey and Rutgers New Jersey Medical School (NJMS) recently discovered a phage display-based approach to halt tumor growth that could be used to treat triple-negative breast cancer – considered the most aggressive type of breast cancer. The findings were published online in the scientific journal eLife.

Using new genomic technology, UCI researchers discover breast cancer cells shift their metabolic strategy in order to metastasize

New discovery in breast cancer could lead to better strategies for preventing the spread of cancer cells to other organs in the body, effectively reducing mortality in breast cancer patients.
According to a study, published today in Nature Cell Biology, breast cancer cells shift their metabolic strategy in order to metastasize. Instead of cycling sugar (glucose) for energy, they preferentially use mitochondrial metabolism.