Recent studies have led to the development of imaging and spinal fluid tests for patients with Alzheimer’s disease. However, the tests can only monitor severe disease. Reporting in ACS Chemical Neuroscience, researchers have now identified a biomarker that could help physicians diagnose AD earlier.
UC San Diego researchers received a $1.3 million grant from the Keck Foundation for a project that could help scientists better understand the role misfolded tau proteins play in causing neurodegenerative diseases like dementia, which may lead to more effective drug therapies.
Researchers used microscopy and machine learning to distinguish tau protein aggregates occurring as part of healthy functions from those occurring in disease