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UrduA new study shows that lung stem cell secretions – specifically exosomes and secretomes – delivered via nebulizer, can help repair lung injuries due to multiple types of pulmonary fibrosis in mice and rats.
Tag: Stem Cell
Mount Sinai Researchers Discover New Approach for Use of Stem Cells to Improve Bone Marrow Transplantation
Mount Sinai researchers have discovered a way to enhance the potency of blood-forming stem cells, potentially opening the door to a new approach for bone marrow transplantation.
UCLA researchers discover new compound that promotes lung health
A molecule identified by UCLA researchers helps maintain a healthy balance of cells in airway and lung tissue. If the compound, so far only studied in isolated human and mouse cells, has the same effect in people, it may lead to new drugs to treat or prevent lung cancer.
Proper heart development all about timing
The University of Chicago Medicine’s Ivan Moskowitz, MD, PhD, and his team are studying why some cells develop into their adult forms more quickly than others, and how issues with that timing can lead to congenital heart disease.
CDI Lab Explores Pathway to Open up Blood Cancer Treatments
The CDI team’s findings could ultimately improve cancer treatments for people of advanced age, like that of adult acute myeloid leukemia (AML)
Allen Institute for Cell Science Extends Agreement with Coriell Institute for Medical Research
The Allen Institute has extended its contract with the Coriell Institute for Medical Research for the storage and distribution of its Allen Cell Collection, a cutting-edge collection of gene-edited human induced pluripotent stem cell lines. This collection was launched in 2016 with five cell lines, and since has grown to include more than 40 lines. The new agreement will continue this relationship for an additional three years.
Six patients with rare blood disease are doing well after gene therapy clinical trial
UCLA researchers are part of an international team that reported the use of a stem cell gene therapy to treat nine people with the rare, inherited blood disease known as X-linked chronic granulomatous disease, or X-CGD. Six of those patients are now in remission and have stopped other treatments. Before now, people with X-CGD – which causes recurrent infections, prolonged hospitalizations for treatment, and a shortened lifespan – had to rely on bone marrow donations for a chance at remission.
Researchers create accurate model of organ scarring using stem cells in a lab
A team led by Dr. Brigitte Gomperts at UCLA has developed a “scar in a dish” model that uses multiple types of cells derived from human stem cells to closely mimic the progressive scarring that occurs in human organs. The researchers used this model to identify a drug candidate that stopped the progression of and even reversed fibrosis in animal models.
New Mayo Clinic studies to be presented at American Society of Hematology meeting
Mayo Clinic researchers will present findings at the American Society of Hematology Annual Meeting Dec. 7–10 in Orlando.
New Mayo Clinic studies to be presented include:
DNA analysis identifies elevated risk factor for myeloma in individuals of African ancestry
Study identifies more precise assessment measures for patients newly diagnosed with chronic lymphocytic leukemia
Researchers develop method to assess cancer-fighting cell therapy’s effectiveness
Researchers identify protein that governs human blood stem cell self-renewal
UCLA scientists have discovered a link between a protein and the ability of human blood stem cells to self-renew. In a study published today in the journal Nature, the team reports that activating the protein causes blood stem cells to self-renew at least twelvefold in laboratory conditions
Stem Cells Don’t Take the Day Off on Thanksgiving
While most of us are enjoying the traditional turkey and pumpkin pie on Thanksgiving Day, employees at Cedars-Sinai will be hand-feeding stem cells their special daily formula, carefully monitoring the incubator temperatures and caring for the cells that may become part of important research that could one day lead to treatments for diseases that have plagued humans for years.
Guarding against a devastating tropical disease
Schistosomiasis is one of the most devastating tropical diseases in the world, second only to malaria in its prevalence. The only treatment currently used is extremely limited in its effectiveness and in who it can help. The Newmark Lab wants to develop something that protects people from being infected in the first place.
‘It’s not about just surviving. It’s about seeing my patients living normally’
Dr. Eugene Chang was 25, recently engaged and halfway through a physical medicine and rehabilitation residency in Vancouver when he started feeling sick. Fatigue, dizziness and nausea took over his normally active lifestyle. Suddenly his bike to work was not so easy.
Three UCLA scientists receive grants totaling more than $18 million
Three researchers at the Eli and Edythe Broad Center of Regenerative Medicine and Stem Cell Research at UCLA have received awards totaling more than $18 million from the California Institute for Regenerative Medicine, the state’s stem cell agency.
Tapeworms need to keep their head to regenerate
Scientists show that the location of stem cells is essential in determining tapeworms’ ability to regenerate.
Stem Cells With ‘Dual Identity’ Linked to Loss of Smell From Sinus Inflammation
In experiments with mice and human tissue samples, Johns Hopkins Medicine researchers report evidence that neuronal stem cells in the part of the nose responsible for the sense of smell transform themselves to perpetuate the long-term inflammation in chronic sinusitis.
A Snapshot in Time: Study Captures Fleeting Cell Differences That Can Alter Disease Risk
In cinema and science fiction, one small change in the past can have major, sometimes life-changing effects in the future. Using a series of snapshots, researchers recently captured such so-called “butterfly effects” in heart muscle cell development, and say this…