Amiodarone used with anticoagulant therapy increases bleeding-related hospitalizations compared with flecainide or sotalol

A cohort study of more than 90,000 older adults diagnosed with atrial fibrillation (Afib) who were treated with anticoagulants found that treatment with amiodarone during apixaban or rivaroxaban use was associated with greater risk for bleeding-related hospitalizations compared to flecainide or sotalol. The findings are published in Annals of Internal Medicine