news, journals and articles from all over the world.
In a bid to understand why mosquitoes may be more attracted to one human than another, Johns Hopkins Medicine researchers say they have mapped specialized receptors on the insects’ nerve cells that are able to fine-tune their ability to detect particularly “welcoming” odors in human skin.
This basic scientific research provides a comprehensive structural framework that should help drug developers rationally design safer drugs to relieve severe pain.
Researchers have identified the first key biological switch that sounds an alarm in plants when plant-eating animals attack. The mechanism will help unlock a trove of new strategies for improved plant health, from countering crop pest damage to engineering more robust global food webs.
As you drift into unconsciousness before a surgery, general anesthetic drugs flowing through your blood are putting you to sleep by binding mainly to a protein in the brain called the ɣ-aminobutyric acid type A (GABAA) receptor. Now UT Southwestern scientists have shown exactly how anesthetics attach to the GABAA receptor and alter its three-dimensional structure, and how the brain can tell the difference between anesthetics and the psychoactive drugs known as benzodiazepines – which also bind to the GABAA receptor. The findings were published online today in the journal Nature.
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