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UrduArticle title: Lipocalin 2 deficiency-induced gut microbiota dysbiosis evokes metabolic syndrome in aged mice Authors: Vishal Singh, Sarah Galla, Rachel M. Golonka, Andrew D. Patterson, Benoit Chassaing, Bina Joe, Matam Vijay-Kumar From the authors: “Overall, the current study demonstrates that…
Tag: Protein
Mealworm shows promise as a good, sustainable food source, study finds
With global food demands rising at an alarming rate, a study led by IUPUI scientists has found new evidence that the yellow mealworm shows promise as alternative source of nutritional protein.
Genetic discovery delivers new hope for aggressive breast cancers
Groundbreaking cancer research by the University of South Australia has identified an invasive protein molecule that could be responsible for some of the most aggressive breast cancers.
Breakthrough led by NUS researchers provides new potential therapies for osteoporosis
Researchers from the National University of Singapore have identified a new avenue to maintain bone health, which opens up new and potentially more effective osteoporosis treatments.
Why Does COVID-19 Impact Only Some Organs, Not Others?
In severe cases of COVID-19, damage can spread beyond the lungs and into other organs, such as the heart, liver, kidney and parts of the neurological system. Beyond these specific sets of organs, however, the virus seems to lack impact. Ernesto Estrada aimed to uncover an explanation as to how it is possible for these damages to propagate selectively rather than affecting the entire body. He discusses his findings in the journal Chaos.
E-waste eating protein creates rare earth elements
Lawrence Livermore National Laboratory (LLNL) researchers, in collaboration with Pennsylvania State University (PSU) and Idaho National Laboratory (INL), have designed a new process, based on a naturally occurring protein, that could extract and purify rare earth elements (REE) from low-grade sources. It could offer a new avenue toward a more diversified and sustainable REE sector for the United States. The protein, lanmodulin, enables a one-step extraction and purification of (REE)s from complex metal mixtures, including electronic waste and coal byproducts.
Targeting SARS-CoV-2 Enzyme with Inhibitors
As the COVID-19 pandemic continues to spread, many researchers are studying epidemiological models to predict its propagation. However, a mathematician and expert in complex systems decided to focus on finding targets within SARS-CoV-2 for new drugs to attack. In the journal Chaos, he discusses the dramatic increase in the sensitivity of the main protease of SARS-CoV-2 to small disturbances, which made him suspect there is a role for inhibitors to play in killing the virus.
New Therapeutic Possibilities on the Horizon—Targeted Protein Destruction Made Better
Scientists open doors to new treatment possibilities by using a metal complex to accelerate serum albumin protein destruction with infrared laser beams
Algae in the Oceans Often Steal Genes from Bacteria
Algae in the oceans often steal genes from bacteria to gain beneficial attributes, such as the ability to tolerate stressful environments or break down carbohydrates for food, according to a Rutgers co-authored study.
The study of 23 species of brown and golden-brown algae, published in the journal Science Advances, shows for the first time that gene acquisition had a significant impact on the evolution of a massive and ancient group of algae and protists (mostly one-celled organisms including protozoa) that help form the base of oceanic food webs.
Composing New Proteins with Artificial Intelligence
Proteins are the building blocks of life and scientists have long studied how to improve them or design new ones. Traditionally, new proteins are created by mimicking existing proteins or manually editing their amino acids. This process is time-consuming, and it is difficult to predict the impact of changing an amino acid. In APL Bioengineering, researchers explore how to create new proteins by using machine learning to translate protein structures into musical scores, presenting an unusual way to translate physics concepts across domains.
Study finds “silent” genetic variations can alter protein folding
New research from the University of Notre Dame shows these silent mutations are worth a closer look.
Study Finds Innate Protein that Restricts HIV Replication by Targeting Lipid Rafts
A recent study from the George Washington University suggests that the innate protein AIBP restricts HIV-1 replications by targeting the lipid rafts the virus relies on.
Are there edible cotton seeds?
Genetic engineering makes cotton seeds safe for human consumption
Breaking Through Computational Barriers to Create Designer Proteins
Using advanced computational methods to find working designs, researchers created six protein pairs in cells.
A heart-healthy protein from bran of cereal crop
Researchers have identified a protein in foxtail millet that can help stave off atherosclerosis in mice genetically prone to the disease. They report their results in ACS’ Journal of Agricultural and Food Chemistry.
Catch and release: MTU biochemists purify proteins with a fishing technique
Protein purification is a multibillion-dollar industry. A new purification process developed by Michigan Tech biochemists, called capture and release (CaRe), is a lot like catch and release fishing. It comes down to the picking the right lure to bait a specific protein and CaRe speeds up protein purification while also lowering costs.
Opening Up DNA to Delete Disease
Protein editorial assistants are clearing the way for cut-and-paste DNA editors, like CRISPR, to access previously inaccessible genes of interest. Opening up these areas of the genetic code is critical to improving CRISPR efficiency and moving toward futuristic, genetic-based assaults on disease. The DNA-binding editorial assistants were devised by a U.S.-based team of bioengineers, who describe their design in APL Bioengineering.
Heart-Function Protein May Help Muscular Dystrophy Patients Live Longer
A Rutgers-led team may have found the key to preventing Duchenne muscular dystrophy (DMD)-related heart disease, the leading cause of death in patients living with the disease
New research shows that consuming mung bean protein can improve physical strength — no exercise required.
New research from Arizona State University shows that consuming mung bean protein can improve physical strength — no exercise required.
FDA approves ultra-low gossypol cottonseed for human, animal consumption
The U.S. Food and Drug Administration has given the green light to ultra-low gossypol cottonseed, ULGCS, to be utilized as human food and in animal feed, something Texas A&M AgriLife researchers have been working on for nearly 25 years.
Scientists Discover New Antibiotic in Tropical Forest
Scientists from Rutgers University and around the world have discovered an antibiotic produced by a soil bacterium from a Mexican tropical forest that may help lead to a “plant probiotic,” more robust plants and other antibiotics. Probiotics, which provide friendlier bacteria and health benefits for humans, can also be beneficial to plants, keeping them healthy and more robust. The new antibiotic, known as phazolicin, prevents harmful bacteria from getting into the root systems of bean plants, according to a Rutgers co-authored study in the journal Nature Communications.
Supercomputing, neutrons unite to unravel structures of intrinsically disordered protein
Using the Titan supercomputer and the Spallation Neutron Source at the Department of Energy’s Oak Ridge National Laboratory, scientists have created the most accurate 3D model yet of an intrinsically disordered protein, revealing the ensemble of its atomic-level structures.
Choices of the Heart: Healthy Foods More Important than Type of Diet to Reduce Heart Disease Risk
In a study published online in the International Journal of Cardiology, researchers at Beth Israel Deaconess Medical Center (BIDMC) examined the effects of three healthy diets emphasizing different macronutrients – carbohydrates, proteins, or unsaturated fats – on a biomarker that directly reflects heart injury. The team found that all three diets reduced heart cell damage and inflammation, consistent with improved heart health.