Sylvester Researchers, Collaborators Seek Answers to Prostate, Breast Cancer Among People of African Ancestry

Cancer Disparities: A new African Cancer Genome Registry at Sylvester Comprehensive Cancer Center in Miami seeks to find reasons for higher prostate and breast cancer rates in people of African ancestry. Dr. Sophia George, co-principal investigator, is available for interviews, as are two breast and prostate cancer study participants.

New Study by Sylvester Investigators Indicates Treatment Patterns, Not Genetics, Drive Prostate Cancer Disparities

A large-scale retrospective analysis by researchers with the Sylvester Comprehensive Cancer Center suggests that differences in care, rather than genetics, likely explain disparities in advanced prostate cancer between men of African and European ancestry. The study of almost 13,000 men with advanced prostate cancer, published today in The Lancet Digital Health is one of the most comprehensive studies to date of prostate cancer disparities between men of these ethnicities.

Researchers find favorable tradeoffs of PSA screening for prostate cancer

University Hospitals’ Jonathan Shoag, MD, and a team of researchers from Case Western Reserve University and the Case Comprehensive Cancer Center, Weill Cornell Medical Center, the Fred Hutchinson Cancer Research Center, and others, set out to assess the tradeoffs of PSA screening using long-term epidemiologic data. “No matter the assumptions,” Shoag said, “the data showed lower numbers than prior estimates, many in the low single digits, for the number needed to treat to prevent a prostate-cancer death. This result was observed in all men, and especially for Black men.” The researchers presented their findings in a late-breaking abstract at the American Urological Association’s annual meeting this month and the study was published May 15 in The New England Journal of Medicine Evidence.