Researchers showed that adding gamification with either competition or support increased physical activity for patients with Type 2 diabetes
Tag: Perelman School of Medicine at the University of Pennsylvania
Penn Medicine to Require All Health System Employees to Receive COVID-19 Vaccine
Philadelphia-Based Top Academic Health System Becomes Nation’s Largest to Mandate Vaccination, Calling for Workforce to Set an Example to End the Pandemic
New Method Identifies Tau Aggregates Occurring in Healthy Body Structures
Researchers used microscopy and machine learning to distinguish tau protein aggregates occurring as part of healthy functions from those occurring in disease
New Emergency Department Program Enables Patients to Recover at Home Safely
Program established at Penn Medicine to improve support for patients after emergency department visits, helping them recover at home instead of the hospital
Text Message Program Shows 60 Percent of Opioid Tablets Unused After Common Procedures
A Penn Medicine new study of how text messaging could inform opioid prescribing practices showed that 60 percent of opioids are left over after orthopaedic and urologic procedures
Study Illuminates the Molecular Details of Lung Development
Findings should empower the search for better treatments for lung diseases
Staff Dedication Key To Patient Satisfaction with Substance Use Treatment Facilities, Study Shows
Researchers at Penn Medicine used machine learning-aided analysis to uncover top positive and negative themes in patient Yelp reviews of substance use treatment facilities
Overlooked Cilium Could Be Genetic Key to Common Diseases
Long thought a vestigial part of human cells, new genetic analysis of the primary cilium shows that it may be tied to common conditions like diabetes and kidney failure
Discovery Illuminates How Thyroid Hormone ‘Dims’ Metabolism
Basic biology finding on thyroid hormone function could lead to new treatments for obesity, diabetes and related disorders
Medication Keeps More Patients with ANCA-Associated Vasculitis in Remission Than Steroids
Avacopan, which targets a receptor that attracts the cells that cause inflammation, was shown to be more effective at keeping patients in remission for a year than prednisone
Penn Medicine Cancer Cell Therapy Pioneer Carl June, MD, Named 2021 Dan David Prize Laureate
International cancer cell therapy pioneer Carl June, MD, the Richard W. Vague Professor in Immunotherapy in the department of Pathology and Laboratory Medicine in the Perelman School of Medicine at the University of Pennsylvania and director of the Center for Cellular Immunotherapies at Penn’s Abramson Cancer Center, has been named a 2021 Dan David Prize Laureate.
Take-At-Home Tests Boost Colorectal Cancer Screening Tenfold for Health Center Serving Minorities
By making it the default to send colorectal cancer screening tests to patients’ homes unless they opted out via text message, screening rates increased by more than 1,000 percent
Stem Cell Study Illuminates the Cause of a Devastating Inherited Heart Disorder
Stem cell study findings show that LMNA gene mutations can disrupt the “identity” of heart muscle cells
Opiate Overdoses Spike in Black Philadelphians, But Drop in White Residents Since COVID-19
New research into opioid overdoses that occurred during the COVID-19 pandemic highlighted new disparities along racial lines that are likely fueled by existing inequality
Patients in Cancer Remission at High Risk for Severe COVID-19 Illness
Patients with inactive cancer and not currently undergoing treatments also face a significantly higher risk of severe illness from COVID-19, a new study from Penn Medicine published online today in JNCI Cancer Spectrum shows.
Target Discovered That Halts Osteoarthritis-Like Knee Cartilage Degeneration
In a mouse study, researchers used nanotechnology and previous knowledge of a protein pathway to significantly reduce knee cartilage degeneration and pain
Cardiac Rehabilitation is Underused Across the Country. One Simple Change Could Fix That.
Making doctors opt out from prescribing cardiac rehabilitation instead of opting in increased referrals by roughly 70 percent
New Statistical Method Exponentially Increases Ability to Discover Genetic Insights
A test of the Sum-Share statistical method using only summary-level data found 1,734 genetic variations associated with cardiovascular-related conditions when just one had previously been likely
Significant Disparities in Telemedicine Use, Especially Among Older and Non-White Patients
Older people as well as minorities, non-English speakers and those with lower incomes face inequities in accessing telemedicine care amid COVID-19
Community Spread of COVID-19 Tied to Patient Survival Rates at Area Hospitals
Discovering wide variation in hospitals’ COVID-19 survival rates, researchers found that the levels of the novel coronavirus in the surrounding community was likely the driving factor
Remote Monitoring Leads to 4x Decline in Returns to Hospital After Joint Replacements
The rate of hospital readmissions for hip and knee replacement patients declined from roughly 12 percent to 3 percent when they were enrolled in a “hovering” program
329 People Injured by Firearms in U.S. Each Day, But for Every Death, Two Survive
Researchers examine trends in fatal and nonfatal firearm injuries to inform prevention strategies, finding that twice as many people who died from gunshots survive
Potential Cellular Target for Eliminating Bone Breakdown in Osteoporosis Found
By disabling a function of a set of cells in mice, researchers appear to have halted the process that breaks down bone, a likely boon for osteoporosis treatment
COVID-19 Patients Survive In-Hospital Cardiac Arrest at Pre-Pandemic Rates
Resuscitation and survival rates for hospitalized COVID-19 patients who have cardiac arrest are much higher than earlier reports of near-zero; variation at the individual hospital level may have affected overall numbers
Penn Medicine and Comcast/Independence Health’s Quil Come Together for Digital Patient Education
Internationally recognized leaders in health care and connectivity partner with Quil platform to customize and enhance care and patient education through video and digital communication
From 84 Days to 5 Hours: Telemedicine Reduces Dermatology Consult Time
Allowing primary care doctors to take photos and send them to dermatologists improved access to specialty care
Trauma Hospitalizations Fall in Philly During COVID-19 Lockdown, But Gun Violence Rises
Non-intentional trauma fell compared to the period before COVID this year, but ratios of gun violence patients increased after stay-at-home orders were implemented, and were high compared to the same timeframe in previous years
Media’s Reporting on Gun Violence Does Not Reflect Reality, Study Finds
When looking at media reports in three cities, half of victims were covered in the news, but a disproportionate amount of attention was given to less common circumstances and victims
Magnetic Field and Hydrogels Could Be Used to Grow New Cartilage
Instead of using synthetic materials, Penn Medicine study shows magnets could be used to arrange cells to grow new tissues
Workplace Wellness Programs Could Improve If More Personalized, Study Shows
In a program that used three different types of behavioral nudges, a study showed significantly different results for people with different personal and psychological characteristics
Yes or No: Forcing a Choice Increased Statin Prescribing for Heart Disease Patients
Adding an “active choice” nudge to the electronic health record increased statin prescribing for patients with heart disease, but not for those “at-risk”
Hydroxychloroquine No More Effective Than Placebo in Preventing COVID-19
Clinical trial shows health care workers in contact with COVID-19 patients who took hydroxychloroquine each day did not reduce their rate of infection
1 in 10 COVID Patients Return to Hospital After Being Sent Home from ER
Penn study finds patients with low pulse oximetry readings or fever were more than three times as likely to require hospitalization after their initial discharge as compared to other COVID patients
Cell Phone Location Used to Estimate COVID-19 Growth Rates
Data shows that coronavirus infection rates were lower in counties where cell phone activity declined at workplaces and increased at home
Chatbots Delivering Psychotherapy Help Decrease Opioid Use After Surgery
A study showed that patients receiving messages from a chatbot used a third fewer opioids after fracture surgery, and their overall pain level fell, too
Perfectly Balanced: The Yin and Yang of Inflammation Controlled By A Single Molecule
Penn Study Reveals A Molecular Mechanism That Helps The Body Mount Perfectly Balanced Responses to Deadly Infections
Penn Researchers Identify New Genetic Cause of a Form of Inherited Neuropathy
Inherited mutations in a gene that keeps nerve cells intact was shown, for the first time, to be a driver of a neuropathy known as Charcot-Marie-Tooth disease. This finding is detailed in a study led by researchers in the Perelman School of Medicine at the University of Pennsylvania, presenting a clearer picture of the disease’s genetic underpinnings that could inform the development of gene therapies to correct it.
Access to Nature Requires Attention When Addressing Community Health Needs
Nature is a tool to address deeply entrenched health disparities; health systems should work to increase nature access, as they have with other social determinants of health
Nuclear Softening Allows Cells to Move Into Dense Tissue, Encouraging Injury Repair
Using an enzyme inhibitor in meniscus cells, a Penn team was able to soften their nucleus and promote access to previously impassible areas
Reddit Reveals Peaks of Public Interest in COVID-19 Topics
Online forums can be used by public health officials to quickly identify topics of public interest during the COVID-19 pandemic and to quell misinformation
Financial Incentives Boost Doctor Training in Opioid Treatment Medication
Offering $750 to emergency medicine physicians exponentially increased those trained to prescribe buprenorphine.
Penn Medicine Announces Appointment of Daniel Yoshor, MD, as Chair of the Department of Neurosurgery
Daniel Yoshor, MD, has been named chair of the department of Neurosurgery in the Perelman School of Medicine at the University of Pennsylvania and vice president of Clinical Integration and Innovation for the University of Pennsylvania Health System.
Penn’s Perelman School of Medicine Ranked 3rd Best Medical School in the United States
The Perelman School of Medicine at the University of Pennsylvania has been ranked #3 among the nation’s medical schools, marking 23 consecutive years the school garnered honors among the top 10 research-oriented medical schools.
Facebook Users Change Their Language Before an Emergency Hospital Visit
The language in Facebook posts becomes less formal and invokes family more often in the lead-up to an emergency room visit.
Releasing Brakes: Potential New Methods for Duchenne Muscular Dystrophy Therapies
Testing of small molecules in mouse models of Duchenne muscular dystrophy shows promise for restoration of muscle structure and function.
Fewer Steroids, No Plasma Exchange: A Change in Treatment for Vasculitis
The insights from the PEXIVAS Trial, a 10-year study, shows treatment for ANCA-associated vasculitis can become much more patient-friendly by using half the typical dose of steroids and no blood plasma exchanges
Patients Stick with Smartphone Activity Trackers Longer Than Wearable Devices
Six months after discharge, smartphone users were 32 percent more likely to continue sending health data to researchers than those using wearables
Penn’s Community Health Worker Program Yields $2.47 for Every $1 Invested Annually by Medicaid
Every dollar spent on patients receiving support from Penn Medicine’s community health worker (CHW) program resulted in an annual return on investment (ROI) of $2.47 for every dollar invested annually by Medicaid, according to a new study published online today in Health Affairs. The savings are generated by reducing hospitalizations.
Penn Study Paves Way for New Vaccines to Protect Infants Against Infections
A new Penn Medicine study puts researchers within closer reach of vaccines that can protect infants against infections by overcoming a mother’s antibodies, which are known to shut down immune defenses initiated by conventional vaccines. That hurdle largely explains why vaccinations for infectious diseases like influenza and measles not given until six to 12 months of age. Findings from the preclinical study were published online today in Science Translational Medicine.
Bystander CPR Less Likely for People Living in Hispanic Neighborhoods Compared to Non-Hispanic Neighborhoods
People living in predominately Hispanic neighborhoods are less likely to receive CPR from a bystander following an out-of-hospital cardiac arrest compared to people living in non-Hispanic neighborhoods, researchers from Penn Medicine and the Duke University of School of Medicine reported in the journal Circulation. This same group also had a lower likelihood of survival.