• After kidney transplantation, natural killer cells of the recipient become active because they miss “self” proteins on donor cells.
• These cells contribute to organ rejection, in addition to traditional modes of rejection involving T cells and antibodies.
Tag: Organ Rejection
Finding a Personalized Approach To Treating Chronic Rejection After Lung Transplantation
By studying the roles of an inflammatory protein and antibodies in chronic rejection after lung transplantation, researchers discover possibilities for new treatments.

Tiny Biological Package Gets Drug Right To The ‘Heart’ Of Transplant Rejection
For patients who receive a heart transplant in the near future, the old adage, “Good things come in small packages,” may become words to live by. In a recent study, researchers at Johns Hopkins Medicine and the National Cancer Institute (NCI) demonstrated in mice that they can easily deliver a promising anti-rejection drug directly to the area surrounding a grafted heart by packaging it within a tiny three-dimensional, protein gel cocoon known as a hydrogel. Best of all, the researchers say that the release of the drug is spread out over time, making it highly regulatable and eliminating the need for daily medication to keep rejection in check.