Mount Sinai-Led Team Builds First Model of the Progression of Acute Myeloid Leukemia using CRISPR

A research team led by the Icahn School of Medicine at Mount Sinai (Icahn Mount Sinai) has built the first cellular model to depict the evolution of acute myeloid leukemia (AML), from its early to late stages. By using gene editing technologies to alter genes that make cells malignant, the team was able to identify potential therapeutic targets for early disease stages. The study was reported in the journal Cell Stem Cell in February.

Mount Sinai Health System Launches Center for Light and Health Research

The clinical research conducted through the Center will investigate how to use light to improve people’s lives by stabilizing their circadian rhythms, the natural internal clock that regulates the body’s sleep-wake cycle. Researchers will study how light, either from daylight or electric indoor light, affects circadian rhythms in various populations, from the very young to the very old, including patients with COVID-19, cancer, Alzheimer’s disease, depression, and other illnesses. The goal is to help abate symptoms and improve their sleep, mental health, and cognition.

Mount Sinai Study Finds Wearable Devices Can Detect COVID-19 Symptoms and Predict Diagnosis

Wearable devices can identify COVID-19 cases earlier than traditional diagnostic methods and can help track and improve management of the disease, according to a Mount Sinai study.

New study finds reinfection by SARS-CoV-2 in healthy young adults is common

MEDIA ADVISORY Paper title: SARS-CoV-2 seropositivity and subsequent infection risk in healthy young adults: a prospective cohort study Corresponding Author:  Stuart C. Sealfon, MD, Professor of Neurology, Neuroscience and Pharmacological Sciences, Icahn School of Medicine at Mount Sinai Bottom Line: Although…

Mount Sinai Researchers Build Models Using Machine Learning Technique to Enhance Predictions of COVID-19 Outcomes

Mount Sinai researchers have published one of the first studies using a machine learning technique called “federated learning” to examine electronic health records to better predict how COVID-19 patients will progress.

Heart Disease and COVID-19: Focusing on Exercise, Mental Health, and Nutrition are Critical for High-Risk Groups

February is American Heart Month and cardiologists from the Mount Sinai Health System are sharing tips on heart disease prevention to lower the risk of heart attack, stroke, and COVID-19.

Mount Sinai Researchers Build Models Using Machine Learning Technique to Enhance Predictions of COVID-19 Outcomes

Mount Sinai researchers have published one of the first studies using federated learning to examine electronic health records to better predict how COVID-19 patients will progress.

Girls Who Are Emotionally Neglected or Severely Sexually Abused When Young Report Riskier Sexual Behaviors in Adolescence

Girls who are emotionally neglected or severely sexually abused early in their lives report riskier sexual behaviors during adolescence, Mount Sinai researchers report. The findings highlight the need—and suggest the potential for tailored approaches—to promote healthy sexual development in vulnerable populations.

Scientists Take Important Step Toward Using Retinal Cell Transplants to Treat Blindness

Retinal cells derived from a cadaver human eye survived when transplanted into the eyes of primate models, an important advance in the development of cell therapy to treat blindness, according to a study published on January 14 in Stem Cell Reports.

Mount Sinai Health System Launches Center for Psychedelic Research

The Icahn School of Medicine at Mount Sinai has launched a new center for psychedelics research. The Center for Psychedelic Psychotherapy and Trauma Research pursues a multipronged clinical and research approach to discovering novel and more efficacious therapies for post-traumatic stress disorder (PTSD), depression, anxiety, and other stress-related conditions in the veteran and civilian population.

Multi-Population Risk Scores Could Improve Risk Prediction for Inflammatory Bowel Diseases, Study Finds

New study illustrates how studying diverse populations can help predict patient outcomes and reduce health disparities

Social media and smartphone app use predicts maintenance of physical activity during Covid-19

  Co-corresponding Authors:  M. Mercedes Perez-Rodriguez, MD, PhD, Assistant Professor of Psychiatry and Agnes Norbury, PhD, Post Doctoral Fellow, both of the Icahn School of Medicine at Mount Sinai Bottom Line: During lockdowns (stay-at-home orders issued in response to the Covid-19…

Celebration of the 10th Anniversary of the Dubin Breast Center Raises $2.3 Million

The Dubin Breast Center of The Tisch Cancer Institute at the Mount Sinai Health System celebrated its 10th anniversary during its annual gala on Monday, December 7, 2020. The evening honored Eva Andersson-Dubin, MD, founder of the Center and a Mount Sinai trustee, and Elisa Port, MD, FACS, the Center’s Director and Chief of Breast Surgery for the Mount Sinai Health System, and raised more than $2.3 million to benefit the Dubin Breast Center. The center is part of The Tisch Cancer Institute, a National Cancer Institute-designated cancer center.

Majority of Pregnant Women Who Tested Positive for COVID-19 Were Asymptomatic, Study Finds

The majority of pregnant women who tested positive for COVID-19 on arrival to the delivery room were asymptomatic, according to a new paper by Mount Sinai researchers.

Mount Sinai Researchers Advance a Universal Influenza Virus Vaccine

A vaccine that induces immune responses to a wide spectrum of influenza virus strains and subtypes has produced strong and durable results in early-stage clinical trials in humans, Mount Sinai researchers have found.

Go Inside the Most Innovative Minds in Science and Medicine on “Real, Smart People,” a New Podcast

Podcast from the Icahn School of Medicine at Mount Sinai offers a glimpse into the real story of how science and medicine moves forward, one smart person at a time.

Mount Sinai Doctors Opens New Location in Yonkers, New York

Mount Sinai Doctors has opened a new location in Yonkers, New York, with services that include primary care, cardiology, neurology, and gastroenterology. The new, state-of-the-art facility is 6,000 square feet and located on the ground floor of the historic Boyce Thompson Center at 1086 North Broadway.

Potential New Therapies for Alzheimer’s Disease are Revealed through Network Modeling of Its Complex Molecular Interactions

Researchers from Mount Sinai and the National Center for Geriatrics and Gerontology in Japan have identified new molecular mechanisms driving late-onset Alzheimer’s Disease.

A Novel Monoclonal Antibody Therapy Cuts LDL Cholesterol by Half in a High-Risk Patient Population, Study Shows

The investigational drug evinacumab reduced low-density lipoprotein (LDL) cholesterol—the so-called “bad” cholesterol—by 50 percent in patients with severe hypercholesterolemia whose condition is resistant to standard treatments, a phase 2 study from the Icahn School of Medicine of Mount Sinai and other global academic sites has found.

What We Know: Mount Sinai to Host COVID-19 Research Symposium

The COVID-19 Research Symposium, hosted by the Mount Sinai Clinical Intelligence Center (MSCIC), is a one-day comprehensive review of advances in research by the Mount Sinai Health System to better understand and treat the coronavirus known as COVID-19.

Mount Sinai’s Valentin Fuster, MD, PhD, Honored by Thai Royal Family for Outstanding Medical Contributions

Thailand’s Royal Family has named Valentin Fuster, MD, PhD, Director of Mount Sinai Heart and Physician-in-Chief of The Mount Sinai Hospital, a winner of the 29th annual Prince Mahidol Award in the field of Medicine.

Mount Sinai Develops Machine Learning Models to Predict Critical Illness and Mortality in COVID-19 Patients

Mount Sinai researchers have developed machine learning models that predict the likelihood of critical events and mortality in COVID-19 patients within clinically relevant time windows.

Most People Mount a Strong Antibody Response to SARS-CoV-2 That Does Not Decline Rapidly

The vast majority of individuals infected with mild-to-moderate COVID 19 mount a robust antibody response that is relatively stable for at least five months, according to research conducted at the Icahn School of Medicine at Mount Sinai and published October 28, in the journal Science.

Mount Sinai Researchers Develop a First-in-Class Humanized Antibody Targeting Bone and Fat

Blocking the Follicle-Stimulating Hormone (FSH) whose levels rise at menopause could solve bone loss and weight gain Senior Author: Mone Zaidi, MD, PhD, MACP, Director of the Mount Sinai Bone Program and Professor of Medicine (Endocrinology, Diabetes and Bone Disease) at…

Ultrasounds Show Impact of COVID-19 on the Heart

International study may guide therapeutic strategies in patients with and without underlying heart conditions

New Theory Sheds Light on How the Environment Influences Human Health

Researchers at Mount Sinai have proposed a groundbreaking new way to study the interaction between complex biological systems in the body and the environment. Their theory suggests the existence of “biodynamic interfaces,” an intermediate entity between the two realms, as opposed to conventional approaches that analyze individual aspects of the interaction between the environment and humans in isolation, according to a paper published in BioEssays in October.

Mount Sinai Doctors Elected to National Academy of Medicine for Contributions to Emergency Medicine and Translational Genetics

Brendan G. Carr, MD, MA, MS, and Judy H. Cho, MD, of the Icahn School of Medicine at Mount Sinai, have been elected to the National Academy of Medicine (NAM).

Mount Sinai Researchers Find That Where People Live Can Impact Their Risk for Common Chronic Conditions Including High Blood Pressure and Depression

The researchers found that a persons’ place of residence substantially influences their risk of uncontrolled chronic disease including high blood pressure and depression

Mount Sinai Selected to Serve as Capacity Building Center and Center of Excellence as Part of the National Cancer Institute’s New Serological Sciences Network

Researchers from the Icahn School of Medicine at Mount Sinai will receive more than $7.3 million from the National Cancer Institute (NCI) as part of the NCI’s new Serological Sciences Network (SeroNet), one of the largest coordinated national efforts to study immunology and SARS-CoV-2, the virus that causes COVID-19. Mount Sinai was selected as one of only four Capacity Building Centers and one of eight Centers of Excellence as part of this new network.

Mount Sinai Health System, Healthcare Association of New York State and Hospital Innovation and Lean Network of New York to Host Conference: “Lean and Innovation in a COVID-19 World”

Virtual conference will highlight Lean innovations that have helped healthcare organizations plan for, manage and mitigate many aspects of the COVID-19 pandemic

Thomas J. Fuchs, DSc, Named Dean of Artificial Intelligence and Human Health and Co-Director of the Hasso Plattner Institute for Digital Health at Mount Sinai

Appointment Advances Health System’s Role as Leader in AI and Digital Health

The Novel Role of Microglia as Modulators of Neurons in the Brain Is Discovered by Mount Sinai Researchers

Findings offer potential target for treating behavioral abnormalities associated with neurodegenerative conditions like Alzheimer’s Disease

Deirdre J. Cohen, MD, MS, Appointed as Director of Gastrointestinal Oncology Program of Mount Sinai Health System

Deirdre J. Cohen, MD, MS, an expert in pancreatic and other gastrointestinal cancers as well as an accomplished clinical trial leader has joined Mount Sinai Health System as Director of the Gastrointestinal (GI) Oncology Program and Medical Director of the Cancer Clinical Trials Office at The Tisch Cancer Institute.

The Tisch Cancer Institute Earns Second Consecutive Designation from National Cancer Institute

The Tisch Cancer Institute at Mount Sinai (TCI) has been awarded $13 million as part of the renewal of its National Cancer Institute Cancer Center Designation, a prestigious distinction that is based on scientific excellence, robust clinical research, and beneficial community impact. The National Cancer Institute rated TCI’s application as “outstanding.”