A research team led by the Icahn School of Medicine at Mount Sinai (Icahn Mount Sinai) has built the first cellular model to depict the evolution of acute myeloid leukemia (AML), from its early to late stages. By using gene editing technologies to alter genes that make cells malignant, the team was able to identify potential therapeutic targets for early disease stages. The study was reported in the journal Cell Stem Cell in February.
Tag: Mount Sinai Health System
Mount Sinai Health System Launches Center for Light and Health Research
The clinical research conducted through the Center will investigate how to use light to improve people’s lives by stabilizing their circadian rhythms, the natural internal clock that regulates the body’s sleep-wake cycle. Researchers will study how light, either from daylight or electric indoor light, affects circadian rhythms in various populations, from the very young to the very old, including patients with COVID-19, cancer, Alzheimer’s disease, depression, and other illnesses. The goal is to help abate symptoms and improve their sleep, mental health, and cognition.
Mount Sinai Study Finds Wearable Devices Can Detect COVID-19 Symptoms and Predict Diagnosis
Wearable devices can identify COVID-19 cases earlier than traditional diagnostic methods and can help track and improve management of the disease, according to a Mount Sinai study.
New study finds reinfection by SARS-CoV-2 in healthy young adults is common
MEDIA ADVISORY Paper title: SARS-CoV-2 seropositivity and subsequent infection risk in healthy young adults: a prospective cohort study Corresponding Author: Stuart C. Sealfon, MD, Professor of Neurology, Neuroscience and Pharmacological Sciences, Icahn School of Medicine at Mount Sinai Bottom Line: Although…
Mount Sinai Researchers Build Models Using Machine Learning Technique to Enhance Predictions of COVID-19 Outcomes
Mount Sinai researchers have published one of the first studies using a machine learning technique called “federated learning” to examine electronic health records to better predict how COVID-19 patients will progress.
Heart Disease and COVID-19: Focusing on Exercise, Mental Health, and Nutrition are Critical for High-Risk Groups
February is American Heart Month and cardiologists from the Mount Sinai Health System are sharing tips on heart disease prevention to lower the risk of heart attack, stroke, and COVID-19.
Mount Sinai Researchers Build Models Using Machine Learning Technique to Enhance Predictions of COVID-19 Outcomes
Mount Sinai researchers have published one of the first studies using federated learning to examine electronic health records to better predict how COVID-19 patients will progress.
Girls Who Are Emotionally Neglected or Severely Sexually Abused When Young Report Riskier Sexual Behaviors in Adolescence
Girls who are emotionally neglected or severely sexually abused early in their lives report riskier sexual behaviors during adolescence, Mount Sinai researchers report. The findings highlight the need—and suggest the potential for tailored approaches—to promote healthy sexual development in vulnerable populations.
Scientists Take Important Step Toward Using Retinal Cell Transplants to Treat Blindness
Retinal cells derived from a cadaver human eye survived when transplanted into the eyes of primate models, an important advance in the development of cell therapy to treat blindness, according to a study published on January 14 in Stem Cell Reports.
Mount Sinai Health System Launches Center for Psychedelic Research
The Icahn School of Medicine at Mount Sinai has launched a new center for psychedelics research. The Center for Psychedelic Psychotherapy and Trauma Research pursues a multipronged clinical and research approach to discovering novel and more efficacious therapies for post-traumatic stress disorder (PTSD), depression, anxiety, and other stress-related conditions in the veteran and civilian population.
Mount Sinai Researchers Identify and Characterize Three Molecular Subtypes of Alzheimer’s Disease
Critical Step Toward Developing Precision Medicine Treatments
Multi-Population Risk Scores Could Improve Risk Prediction for Inflammatory Bowel Diseases, Study Finds
New study illustrates how studying diverse populations can help predict patient outcomes and reduce health disparities
Royalty Pharma Donates $1,000,000 To Support Mount Sinai’s COVID-19 Patient Care and Clinical Research
Royalty Pharma today announced a charitable contribution by Royalty Pharma in the amount of $1,000,000 to Mount Sinai Health System.
Social media and smartphone app use predicts maintenance of physical activity during Covid-19
Co-corresponding Authors: M. Mercedes Perez-Rodriguez, MD, PhD, Assistant Professor of Psychiatry and Agnes Norbury, PhD, Post Doctoral Fellow, both of the Icahn School of Medicine at Mount Sinai Bottom Line: During lockdowns (stay-at-home orders issued in response to the Covid-19…
Celebration of the 10th Anniversary of the Dubin Breast Center Raises $2.3 Million
The Dubin Breast Center of The Tisch Cancer Institute at the Mount Sinai Health System celebrated its 10th anniversary during its annual gala on Monday, December 7, 2020. The evening honored Eva Andersson-Dubin, MD, founder of the Center and a Mount Sinai trustee, and Elisa Port, MD, FACS, the Center’s Director and Chief of Breast Surgery for the Mount Sinai Health System, and raised more than $2.3 million to benefit the Dubin Breast Center. The center is part of The Tisch Cancer Institute, a National Cancer Institute-designated cancer center.
Artificial Intelligence Algorithm Can Predict Outcomes of COVID-19 Patients With Mild Symptoms in Emergency Rooms
Technology may lead to quicker triage and treatment based on patient data and scans
Majority of Pregnant Women Who Tested Positive for COVID-19 Were Asymptomatic, Study Finds
The majority of pregnant women who tested positive for COVID-19 on arrival to the delivery room were asymptomatic, according to a new paper by Mount Sinai researchers.
Mount Sinai Researchers Advance a Universal Influenza Virus Vaccine
A vaccine that induces immune responses to a wide spectrum of influenza virus strains and subtypes has produced strong and durable results in early-stage clinical trials in humans, Mount Sinai researchers have found.
Go Inside the Most Innovative Minds in Science and Medicine on “Real, Smart People,” a New Podcast
Podcast from the Icahn School of Medicine at Mount Sinai offers a glimpse into the real story of how science and medicine moves forward, one smart person at a time.
Mount Sinai Doctors Opens New Location in Yonkers, New York
Mount Sinai Doctors has opened a new location in Yonkers, New York, with services that include primary care, cardiology, neurology, and gastroenterology. The new, state-of-the-art facility is 6,000 square feet and located on the ground floor of the historic Boyce Thompson Center at 1086 North Broadway.
Three Mount Sinai Ophthalmologists Receive Prestigious Achievement Awards
Multiple honors recognize leadership and exemplary scientific and educational contributions
Potential New Therapies for Alzheimer’s Disease are Revealed through Network Modeling of Its Complex Molecular Interactions
Researchers from Mount Sinai and the National Center for Geriatrics and Gerontology in Japan have identified new molecular mechanisms driving late-onset Alzheimer’s Disease.
Arnhold Institute for Global Health to Host Mount Sinai World AIDS Day
The Arnhold Institute for Global Health at the Icahn School of Medicine Mount Sinai will host a virtual event on World AIDS Day.
Mount Sinai Health System Joins Thousands of Top U.S. Hospitals Encourage Everyone to #MaskUp
Growing numbers of COVID-19 cases and deaths are troubling; facemasks can slow the trend
Mount Sinai Cardiologist Awarded $2.9 Million NIH Grant to Advance Work with Stem Cells and Heart Repair after Heart Attack
Research may lead to identifying novel therapies for cardiac patients
Mount Sinai Heart Awarded Transcatheter Valve Certification by American College of Cardiology
Only program in New York City to receive prestigious recognition
A Novel Monoclonal Antibody Therapy Cuts LDL Cholesterol by Half in a High-Risk Patient Population, Study Shows
The investigational drug evinacumab reduced low-density lipoprotein (LDL) cholesterol—the so-called “bad” cholesterol—by 50 percent in patients with severe hypercholesterolemia whose condition is resistant to standard treatments, a phase 2 study from the Icahn School of Medicine of Mount Sinai and other global academic sites has found.
Diabetes Drug Can Treat and Reverse Heart Failure and Reduce Hospitalizations
Mount Sinai clinical trial results could help lead to FDA approval
New Insights Into Facial Birth Defects Are Revealed by Mount Sinai Researchers
Mount Sinai researchers have revealed new insights into how the body regulates craniofacial development in newborns, which can sometimes lead to birth defects such as cleft lip or palate.
What We Know: Mount Sinai to Host COVID-19 Research Symposium
The COVID-19 Research Symposium, hosted by the Mount Sinai Clinical Intelligence Center (MSCIC), is a one-day comprehensive review of advances in research by the Mount Sinai Health System to better understand and treat the coronavirus known as COVID-19.
Mount Sinai’s Valentin Fuster, MD, PhD, Honored by Thai Royal Family for Outstanding Medical Contributions
Thailand’s Royal Family has named Valentin Fuster, MD, PhD, Director of Mount Sinai Heart and Physician-in-Chief of The Mount Sinai Hospital, a winner of the 29th annual Prince Mahidol Award in the field of Medicine.
Study of Nearly 2,000 Marine Recruits Reveals Asymptomatic SARS-CoV-2 Transmission Among Young Adults During Supervised Quarantine
Results suggest the need for widespread surveillance testing to reduce COVID-19 transmission in group settings
Mount Sinai Develops Machine Learning Models to Predict Critical Illness and Mortality in COVID-19 Patients
Mount Sinai researchers have developed machine learning models that predict the likelihood of critical events and mortality in COVID-19 patients within clinically relevant time windows.
Mount Sinai Doctors Faculty Practice Recognized by Press Ganey for Patient Experience Excellence
2020 Recipient of Pinnacle of Excellence Award
Study Finds 1.7 Million New Yorkers Have Been infected with SARS-Cov-2 and Virus was in NYC Earlier than Reported
The virus that causes COVID-19 was present in New York City long before the city’s first case of the disease was confirmed on March 1
Most People Mount a Strong Antibody Response to SARS-CoV-2 That Does Not Decline Rapidly
The vast majority of individuals infected with mild-to-moderate COVID 19 mount a robust antibody response that is relatively stable for at least five months, according to research conducted at the Icahn School of Medicine at Mount Sinai and published October 28, in the journal Science.
Heart Failure Patients With COVID-19 Nearly Twice as Likely to Die and at Triple the Risk of Intubation Compared to Those Without Pre-Existing Heart Condition
Results may lead to closer monitoring of heart failure patients in hospital and at home
Mount Sinai Researchers Develop a First-in-Class Humanized Antibody Targeting Bone and Fat
Blocking the Follicle-Stimulating Hormone (FSH) whose levels rise at menopause could solve bone loss and weight gain Senior Author: Mone Zaidi, MD, PhD, MACP, Director of the Mount Sinai Bone Program and Professor of Medicine (Endocrinology, Diabetes and Bone Disease) at…
Ultrasounds Show Impact of COVID-19 on the Heart
International study may guide therapeutic strategies in patients with and without underlying heart conditions
New Theory Sheds Light on How the Environment Influences Human Health
Researchers at Mount Sinai have proposed a groundbreaking new way to study the interaction between complex biological systems in the body and the environment. Their theory suggests the existence of “biodynamic interfaces,” an intermediate entity between the two realms, as opposed to conventional approaches that analyze individual aspects of the interaction between the environment and humans in isolation, according to a paper published in BioEssays in October.
Mount Sinai Doctors Elected to National Academy of Medicine for Contributions to Emergency Medicine and Translational Genetics
Brendan G. Carr, MD, MA, MS, and Judy H. Cho, MD, of the Icahn School of Medicine at Mount Sinai, have been elected to the National Academy of Medicine (NAM).
Mount Sinai Study Shows Novel Surgical Technique For Prostate Cancer Improves Urinary Continence
Mount Sinai study described a novel surgical technique, the RARP “hood technique” which showed a reduction in postoperative urinary incontinence and facilitated early return of continence in patients with localized prostate cancer.
Mount Sinai Researchers Find That Where People Live Can Impact Their Risk for Common Chronic Conditions Including High Blood Pressure and Depression
The researchers found that a persons’ place of residence substantially influences their risk of uncontrolled chronic disease including high blood pressure and depression
Mount Sinai Selected to Serve as Capacity Building Center and Center of Excellence as Part of the National Cancer Institute’s New Serological Sciences Network
Researchers from the Icahn School of Medicine at Mount Sinai will receive more than $7.3 million from the National Cancer Institute (NCI) as part of the NCI’s new Serological Sciences Network (SeroNet), one of the largest coordinated national efforts to study immunology and SARS-CoV-2, the virus that causes COVID-19. Mount Sinai was selected as one of only four Capacity Building Centers and one of eight Centers of Excellence as part of this new network.
Mount Sinai Health System, Healthcare Association of New York State and Hospital Innovation and Lean Network of New York to Host Conference: “Lean and Innovation in a COVID-19 World”
Virtual conference will highlight Lean innovations that have helped healthcare organizations plan for, manage and mitigate many aspects of the COVID-19 pandemic
Thomas J. Fuchs, DSc, Named Dean of Artificial Intelligence and Human Health and Co-Director of the Hasso Plattner Institute for Digital Health at Mount Sinai
Appointment Advances Health System’s Role as Leader in AI and Digital Health
The Novel Role of Microglia as Modulators of Neurons in the Brain Is Discovered by Mount Sinai Researchers
Findings offer potential target for treating behavioral abnormalities associated with neurodegenerative conditions like Alzheimer’s Disease
Deirdre J. Cohen, MD, MS, Appointed as Director of Gastrointestinal Oncology Program of Mount Sinai Health System
Deirdre J. Cohen, MD, MS, an expert in pancreatic and other gastrointestinal cancers as well as an accomplished clinical trial leader has joined Mount Sinai Health System as Director of the Gastrointestinal (GI) Oncology Program and Medical Director of the Cancer Clinical Trials Office at The Tisch Cancer Institute.
Icahn School of Medicine at Mount Sinai and Leica Microsystems Establish Center of Excellence in Microscopy
The new Center will support a mission to drive new discoveries and insights from scientific research performed using state-of-the-art imaging systems.
The Tisch Cancer Institute Earns Second Consecutive Designation from National Cancer Institute
The Tisch Cancer Institute at Mount Sinai (TCI) has been awarded $13 million as part of the renewal of its National Cancer Institute Cancer Center Designation, a prestigious distinction that is based on scientific excellence, robust clinical research, and beneficial community impact. The National Cancer Institute rated TCI’s application as “outstanding.”