How not to use brain scans in neuroscience

The idea that a lone snapshot of a brain can tell you about an individual’s personality or mental health has been the basis of decades of neuroscience studies. That approach was punctured by a paper in Nature earlier this year showing that scientists have massively underestimated how large such studies must be to produce reliable findings. At the center of the research is MRI (magnetic resonance imaging) brain scans. Reaching that conclusion required getting a far broader view of the field than was possible until recently. Along with colleagues at a number of institutions as well as his advisor, Pitt Professor of Psychiatry Beatriz Luna, Tervo-Clemmens combined three recent publicly available studies that together included MRI data from around 50,000 participants.