Mount Sinai Study Uncovers Inflammatory Markers that May Predict a Response in Certain Patients to COVID-19 Immunotherapies

Researchers at The Tisch Cancer Institute uncovered inflammatory markers that may predict which COVID-19 patients are more likely to respond to therapies like the anti-cancer drug pacritinib, according to phase 2 trial results published in JAMA Network Open in December.

New technique may lead to safer stem cell transplants

Studying mice, researchers at Washington University School of Medicine in St. Louis have developed a method of stem cell transplantation that does not require radiation or chemotherapy. Instead, the strategy takes an immunotherapeutic approach, combining the targeted elimination of blood-forming stem cells in the bone marrow with immune-modulating drugs to prevent the immune system from rejecting the new donor stem cells.

Study Finds Cycling JAK Inhibitors Effective Option for Patients with Difficult-to-Treat RA

New research presented this week at ACR Convergence, the American College of Rheumatology’s annual meeting, shows that people with difficult-to-treat rheumatoid arthritis who do not have success with JAK inhibitor can achieve success either cycling to other JAKi or switching to a biologic drug.