ROCKVILLE, MD – The virus that causes COVID-19, called SARS-CoV-2, uses its spike protein in order to stick to and infect our cells. The final step for the virus to enter our cells is for part of its spike protein to act like a twist tie, forcing the host cell’s outer membrane to fuse with the virus. Kailu Yang, in the lab of Axel Brunger, colleagues at Stanford University, and collaborators at University of California Berkely, Harvard Medical School, and University of Finland have generated a molecule based on the twisted part of the spike protein (called HR2), which sticks itself onto the virus and prevents the spike protein from twisting.
Tag: HHMI
New HHMI Program Pledges $1.5 Billion for Outstanding Early Career Faculty Committed to Diversity, Equity, and Inclusion
The Freeman Hrabowski Scholars Program will support up to 150 early career scientists for their research and their efforts to create labs in which everyone can thrive. Applications to the program are open now.
Mount Sinai Neurobiologist Selected as a Howard Hughes Medical Institute Investigator
The Howard Hughes Medical Institute (HHMI) has selected Ian Maze, PhD, Associate Professor of Neuroscience, and Pharmacological Sciences, at the Icahn School of Medicine at Mount Sinai, as an HHMI Investigator.
Sloan Kettering Institute’s Dana Pe’er Named Howard Hughes Medical Institute Investigator
Dana Pe’er, PhD, computational biologist and lab head at Memorial Sloan Kettering Cancer Center’s (MSK) Sloan Kettering Institute (SKI), is one of 33 biomedical researchers named a Howard Hughes Medical Institute (HHMI) investigator today.
COVID-19 Immunity May Last Six Months or More
People who have recovered from coronavirus can make potent antibodies to SARS-CoV-2 that evolve in the months after infection. These antibodies may be evolving in response to residual viral antigen hidden in the gut.
Clayton S. Rose Elected Chair of HHMI’s Trustees
Rose, President of Bowdoin College and a longtime Howard Hughes Medical Institute Trustee, will succeed Kurt L. Schmoke as Chair of the Trustees.