A study in mice finds treatment with a molecule called MCB-613 repairs heart tissue after a severe heart attack, preventing damage that can lead to heart failure. The findings are being presented virtually at ENDO 2021, the Endocrine Society’s annual meeting.
Tag: Heart Attack
Model Identifies Risk of Serious Complications Following Surgery
A web-based tool developed by Jefferson researchers predicts individualized risk for stroke, other grave post-surgical complications
Instant death from heart attack more common in people who do not exercise
An active lifestyle is linked with a lower chance of dying immediately from a heart attack, according to a study published today in the European Journal of Preventive Cardiology, a journal of the European Society of Cardiology (ESC).1
Cardiac Calcium Scoring Saves One Man’s Life
The imaging procedure (called a CT Calcium Scoring scan) a CT or CAT scan, is a preventive cardiovascular screening test that is painless and noninvasive and takes only 10 minutes. Electron Beam Computed Tomography (EVCT) beam detects and measures the amount of calcium in the heart’s arteries. The more calcium that is present, the greater the likelihood of developing heart disease or having a heart attack or stroke. The test provides patients and their health care providers with the most accurate available “picture” of their current risk of developing heart disease or experiencing a heart attack.
The Medical Minute: Is it a panic attack or a heart attack?
Panic attacks aren’t deadly, but heart attacks kill. That’s why knowing the difference could save a life.
Dementia Drug Reduces Heart Attack Risk in Postmenopausal Mice
Article title: Increased cholinergic activity under conditions of low estrogen leads to adverse cardiac remodeling Authors: Vanessa P. Teixeira, Kiany Miranda, Sergio Scalzo, Cibele Rocha-Resende, Mário Morais Silva, Geisa C. S. V. Tezini, Marcos B. Melo Melo MB, Fernando Pedro…
Heart Disease and COVID-19: Focusing on Exercise, Mental Health, and Nutrition are Critical for High-Risk Groups
February is American Heart Month and cardiologists from the Mount Sinai Health System are sharing tips on heart disease prevention to lower the risk of heart attack, stroke, and COVID-19.
Mayo Clinic study indicates age has distinct influences on sex-related outcomes after heart attack
Approximately 1.5 million heart attacks and strokes occur every year in men and women in the U.S. Sex and age play a large part in who experiences a heart attack, the methods used to treat these heart attacks, and the eventual post hospital outcomes of the people who experience heart attacks.
Cardiac Rehabilitation is Underused Across the Country. One Simple Change Could Fix That.
Making doctors opt out from prescribing cardiac rehabilitation instead of opting in increased referrals by roughly 70 percent
Story Ideas from Johns Hopkins Medicine
During the COVID-19 pandemic, Johns Hopkins Medicine Media Relations is focused on disseminating current, accurate and useful information to the public via the media. As part of that effort, we are distributing our “COVID-19 Tip Sheet: Story Ideas from Johns Hopkins” every other Tuesday.
Research News Tip Sheet: Story Ideas From Johns Hopkins Medicine
During the COVID-19 pandemic, Johns Hopkins Medicine Media Relations is focused on disseminating current, accurate and useful information to the public via the media. As part of that effort, we are distributing our “COVID-19 Tip Sheet: Story Ideas from Johns Hopkins” every other Tuesday.
Mount Sinai Cardiologist Awarded $2.9 Million NIH Grant to Advance Work with Stem Cells and Heart Repair after Heart Attack
Research may lead to identifying novel therapies for cardiac patients
Virginia Tech scientists provide new evidence of elusive electrical pathway in the heart
The research team discovered it could improve irregular heart rhythms – even when the heart’s blood supply was completely shut off – by altering concentrations of common electrolytes in the bloodstream.
Election stress can hurt your heart
Election stress is in full effect and it can take a heavy toll on our heart health. Like the death of a loved one or a natural disaster, the election is on par with other traumatic episodes that can trigger heart stress and exacerbate pre-existing heart conditions.
Ultrasounds Show Impact of COVID-19 on the Heart
International study may guide therapeutic strategies in patients with and without underlying heart conditions
Fractional Flow Reserve Derived from Computed Tomography Coronary Angiography Did Not Significantly Reduce Costs But Reduced Rates of Invasive Coronary Angiography
In the FORECAST randomized clinical trial, the use of fractional flow reserve management derived from computed tomography (FFRCT) did not significantly reduce costs but did reduce the use of invasive coronary angiography (ICA).
Combined FFR and OCT Imaging Can Improve Accuracy of High-Risk Lesion Identification in Patients with Diabetes
Data from COMBINE (OCT-FFR) found that the use of FFR combined with OCT imaging can help improve the accuracy of high-risk lesion identification in patients with diabetes. Findings were reported today at TCT Connect, the 32nd annual scientific symposium of the Cardiovascular Research Foundation (CRF). TCT is the world’s premier educational meeting specializing in interventional cardiovascular medicine.
Pilot Randomized Trial Demonstrates that PCI of Non-Flow-Limiting Vulnerable Plaques May be Safe with Favorable Long-Term Clinical Outcomes
New data from PROSPECT ABSORB, a pilot randomized trial of percutaneous coronary intervention (PCI) of non-flow-limiting vulnerable plaques in native coronary arteries, found that PCI was safe, substantially enlarged follow-up lumen areas, and was associated with favorable long-term clinical outcomes.
New Approach Helps EMTs Better Assess Chest Pain en Route to Hospital
A study conducted at Wake Forest Baptist Health shows that on-scene use of a new protocol and advanced diagnostic equipment can help paramedics better identify patients at high risk for adverse cardiac events.
Uncovering the Genetics Behind Heart Attacks That Surprise Young, Healthy Women
New genetic research finds spontaneous coronary artery dissection, or SCAD, heart attacks may be more similar to different diseases than to other heart attacks.
Online searches for ‘chest pain’ rise, emergency visits for heart attack drop amid COVID
A study of search engine queries addressed the question of whether online searches for chest pain symptoms correlated to reports of fewer people going to the emergency department with acute heart problems during the COVID-19 pandemic.
Clear Link Between Heart Disease and COVID-19, But Long-Term Implications Unknown, Researchers Find in Review of Published Studies
In a prospectus review published this week in the Journal of Molecular and Cellular Cardiology, Kirk U. Knowlton MD, from the Intermountain Healthcare Heart Institute in Salt Lake City, examined more than 100 published studies related to COVID-19 and its effects on the heart.
Scientists proposed a new approach to assessing platelet activation risk
Russian researchers have developed a new method for assessing individual risks of intravascular platelet activation. The latter plays a crucial role in the development of various serious clinical situations such as heart attacks and strokes. The range of circumstances that may be associated with the development of intravascular coagulation is currently actively investigated worldwide. In particular, the onset of intravascular coagulation may be triggered by temporary spikes in blood pressure.
CRF Will Hold Free Online Seminar on Heart Disease Warning Signs
The Cardiovascular Research Foundation (CRF) will hold a free online seminar, “Get Heart Smart,” on August 24 hosted by Drs. Nisha Jhalani and Ajay Kirtane, renowned academic cardiologists from NewYork-Presbyterian/Columbia University Irving Medical Center. The seminar, part of a series of “Mini Med Schools” conducted by the CRF Women’s Heart Health Initiative, will focus on common heart disease symptoms, when to talk to your doctor, and when to seek emergency care.
Brooklyn Heart Patient Saves Own Life Amid COVID-19
Ann Apasewicz was hesitant to seek care at the height of the pandemic, but consulting her NYU Langone Hospital—Brooklyn doctor saved her life
Better Measure of ‘Good Cholesterol’ Can Gauge Heart Attack And Stroke Risk in Some Populations
DALLAS – June 22, 2020 – For decades, high-density lipoprotein (HDL) cholesterol has been dubbed “good cholesterol” because of its role in moving fats and other cholesterol molecules out of artery walls. People with higher HDL cholesterol levels tend to have lower rates of cardiovascular disease, studies have shown.
World’s smallest imaging device has heart disease in focus
A team of researchers led by the University of Adelaide and University of Stuttgart has used 3D micro-printing to develop the world’s smallest, flexible scope for looking inside blood vessels.
New antiplatelet drug shows promise for treating heart attack
Researchers have developed a new drug that prevents blood clots without causing an increased risk of bleeding, a common side effect of all antiplatelet medications currently available. A new study published in the journal Science Translational Medicine describes the drug and its delivery mechanisms and shows that the drug is also an effective treatment for heart attack in animal models.
BREAST CANCER DEADLIER IN HEART ATTACK SURVIVORS
Breast Cancer patients are 60 percent more likely to die of cancer after surviving a heart attack, a new study finds.
Better Measure of ‘Good Cholesterol’ Can Gauge Heart Attack And Stroke Risk in Some Populations
DALLAS – June 22, 2020 – For decades, high-density lipoprotein (HDL) cholesterol has been dubbed “good cholesterol” because of its role in moving fats and other cholesterol molecules out of artery walls. People with higher HDL cholesterol levels tend to have lower rates of cardiovascular disease, studies have shown.
Blocking brain signals detected in the kidney could help unlock future treatments for kidney failure, heart disease, and stroke
Scientists have discovered an important cell signalling pathway in the kidney which if stopped, could hold the key to treating chronic kidney disease as well as other deadly conditions, including heart attack and stroke.
First Do No Harm – Researchers Urge Halt in Prescribing Hydroxycholoroquine for COVID-19
Researchers urge a moratorium on prescribing chloroquine or hydroxychloroquine, with or without azithromycin, to treat or prevent COVID-19, and caution that the reassuring safety profile of hydroxychloroquine may be more apparent than real. Safety data derive from decades of prescriptions by clinicians, primarily for their patients with lupus and rheumatoid arthritis, both of which are of greater prevalence in younger and middle age women, who are at very low risk of fatal heart outcomes due to hydroxychloroquine.
Study Explores Role of Extracellular Vesicles in Tissue Repair after Heart Attack
Article title: CDC-derived extracellular vesicles reprogram inflammatory macrophages to an arginase 1-dependent pro-angiogenic phenotype Authors: Kyle I. Mentkowski, Asma Mursleen, Jonathan D. Snitzer, Lindsey M. Euscher, Jennifer K. Lang From the authors: “Our study was designed to gain mechanistic insight into the…
Precision medicine guides choice of better drug therapy in severe heart disease
Is personalized medicine cost-effective? Researchers have answered that question for one medical treatment, genotype-guided antiplatelet therapy for acute coronary syndrome patients with PCI. Their study uses pharmacogenomics and economic analysis of real-world clinical data.
Heart attack, stroke risk declines among people with diabetes
The rate of heart attacks, strokes and other cardiovascular complications has improved among people with diabetes over the past 20 years, narrowing the gap in cardiovascular mortality rates between individuals with and without diabetes, according to a new study published in the Endocrine Society’s Journal of Clinical Endocrinology & Metabolism.
UC San Diego Health Emergency Departments Equipped to Safely Treat all Patients During Global Pandemic
With increased awareness and fear of COVID-19, some patients have refrained from going to the Emergency Department, even when most needed. Doctors at UC San Diego Health wish to reassure the public that fear of coronavirus should not deter patients…
Smoking Increases Risk for COVID-19 Complications—So It’s a Great Time to Quit
It is well known that smoking results in worse outcomes in people with pneumonia or influenza, and we are learning that smoking can pose significant risks in those with COVID-19.
Heart attack on a chip: scientists model conditions of ischemia on a microfluidic device
Researchers invented a microfluidic chip containing cardiac cells that is capable of mimicking hypoxic and other conditions following a heart attack. The chip can be used to monitor electrophysiological and molecular response of the cells to heart attack conditions in real time.
For Every 50 Smokers – One Non-Smoker Dies from Secondhand Smoke Exposure
New data analysis could change smoking policies worldwide to protect non-smokers and reduce their risk
Mayo Clinic research discovers how stem cells repair damage from heart attacks
Mayo Clinic researchers have uncovered stem cell-activated mechanisms of healing after a heart attack. Stem cells restored cardiac muscle back to its condition before the heart attack, in turn providing a blueprint of how stem cells may work.
Researchers Discover a New Diet-Associated Gut-Microbe Metabolite Linked to Cardiovascular Disease
Cleveland Clinic researchers have identified a gut microbe generated byproduct – phenylacetylglutamine (PAG) – that is linked to development of cardiovascular disease, including heart attack, stroke and death. The study was published in Cell today.
Could This Plaque Identifying Toothpaste Prevent a Heart Attack or Stroke?
For decades, researchers have suggested a link between oral health and inflammatory diseases affecting the entire body – in particular, heart attacks and strokes. Results of a randomized pilot trial of Plaque HD®, the first toothpaste that identifies plaque so that it can be removed with directed brushing, showed that it produced a statistically significant reduction in C-reactive protein, a sensitive marker for future risks of heart attacks and strokes, among those with elevations at baseline.
Researchers Challenge New Guidelines on Aspirin in Primary Prevention
New guidelines recommend aspirin use in primary prevention for people ages 40 to 70 years old who are at higher risk of a first cardiovascular event, but not for those over 70. Yet, people over 70 are at higher risks of cardiovascular events than those under 70. As a result, health care providers are understandably confused about whether or not to prescribe aspirin for primary prevention of heart attacks or strokes, and if so, to whom.
Mayo Clinic study looks at changes in patient characteristics, outcomes for coronary revascularization over 14-year period
The most common type of heart disease ― coronary artery disease ― affects 6.7% of adults and accounts for 20% of 2 in 10 deaths of adults under age 65. The condition builds over time as inflammation and cholesterol-containing plaques settle in the heart’s arteries, where they can eventually cause narrowing and blockages that lead to a heart attack.
Panic Attack vs. Heart Attack: How to Tell the Difference
Patricia Tung, MD, a cardiologist at BIDMC, outlines the key differences between a panic attack and a heart attack.
New Research Supports Initial Conservative Management of Stable Coronary Artery Disease
New study results confirm that guideline-directed medical therapy is as effective as more invasive procedures at preventing death, stroke, and heart attack in patients with stable coronary artery disease (CAD).
The study results suggest that guideline-directed medical therapy should be the initial treatment strategy for patients with stable CAD.
The study results validate the evidence-based, guideline-directed, conservative treatment approach that the cardiovascular specialists at Nuvance Health have always used to treat CAD.
Cleveland Clinic Survey: Most Americans Don’t know Heart Disease Is Leading Cause of Death in Women
A Cleveland Clinic survey finds that although heart disease is the leading cause of death in the United States, 68% of Americans do not know it’s the foremost killer of women.
According to the survey, many Americans incorrectly thought breast cancer was the leading cause of death in women, with men especially likely to think this (44% vs. 33%). Among Millennials, 80% could not identify heart disease as the leading cause of death in women. Heart disease accounts for one in every four deaths in the U.S.
$1 million will help mend a broken heart
Every 40 seconds, a person dies from heart disease in the United States, making it the single leading cause of death in that country s well as worldwide. But what if all those damaged hearts could be repaired with the flick of a switch? A $1 million international study led by the University of South Australia is hoping to do just that.
Aspirin’s health benefits under scrutiny
Taking a baby aspirin every day to prevent a heart attack or stroke should no longer be recommended to patients who haven’t already experienced one of these events.
Stem Cell Therapy Helps Broken Hearts Heal in Unexpected Way
A study in Nature shows stem cell therapy helps hearts recover from a heart attack, although not for the biological reasons originally proposed two decades ago that today are the basis of ongoing clinical trials. The study reports that injecting living or even dead heart stem cells into the injured hearts of mice triggers an acute inflammatory process, which in turn generates a wound healing-like response to enhance the mechanical properties of the injured area.